GOLPH3L and FAM3C

Number of citations of the paper that reports this interaction (PubMedID 34473204)
68

Data Source:
BioGRID (pull down)

		GOLPH3L	FAM3C
Description		golgi phosphoprotein 3 like	FAM3 metabolism regulating signaling molecule C
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Golgi Cisterna Golgi Cisterna Membrane Trans-Golgi Network Membrane	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-4-phosphate Binding Cargo Adaptor Activity	Cytokine Activity Protein Binding Carbohydrate Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Golgi To Plasma Membrane Protein Transport Golgi Vesicle Budding Positive Regulation Of Protein Secretion Protein Targeting To Golgi Apparatus	Inflammatory Response Epidermal Cell Differentiation Gene Expression Neutrophil Differentiation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Keratinocyte Proliferation ERK1 And ERK2 Cascade
Pathways			Platelet degranulation
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) Body mass index ( 26426971) Caffeine consumption from coffee ( 33287642) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Chronotype ( 30696823) Keratinocyte cancer (MTAG) ( 31174203) Morning person ( 30696823) Neutrophil percentage of white cells ( 27863252) Prostate cancer ( 25217961) Refractive error ( 32231278) Rhegmatogenous retinal detachment ( 23585552) Triglyceride levels ( 32203549) Urate levels ( 31578528)	Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 28869591 30598549) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)
Interacting Genes		26 interacting genes: ARL6IP1 B4GALT4 C1GALT1 CANT1 DIPK2A EBAG9 EXT1 FAM20B FAM3C GALNT2 GALNT6 GALNT7 GCNT1 GLG1 GLT8D1 GOLIM4 GOLM2 HTT LNX1 MAN1B1 MGAT2 PGAP4 POMGNT1 TPST1 TPST2 ZDHHC17	50 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GOLPH3 GOLPH3L GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35H1 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2
Entrez ID		55204	10447
HPRD ID		17048	12270
Ensembl ID		ENSG00000143457	ENSG00000196937
Uniprot IDs		Q9H4A5	Q92520
PDB IDs			5LC2
Enriched GO Terms of Interacting Partners?		Golgi Apparatus Golgi Membrane Glycoprotein Metabolic Process Glycosyltransferase Activity Glycoprotein Biosynthetic Process Protein Glycosylation Macromolecule Glycosylation Glycosylation Carbohydrate Derivative Metabolic Process Carbohydrate Derivative Biosynthetic Process Protein O-linked Glycosylation Transferase Activity Protein O-linked Glycosylation Via N-acetyl-galactosamine Protein Modification Process Protein Metabolic Process Macromolecule Biosynthetic Process Polypeptide N-acetylgalactosaminyltransferase Activity Membrane Proteoglycan Biosynthetic Process Protein-tyrosine Sulfotransferase Activity Carbohydrate Binding Proteoglycan Metabolic Process Macromolecule Metabolic Process Manganese Ion Binding Golgi Cisterna Membrane 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Carbohydrate Metabolic Process Sulfation Acetylglucosaminyltransferase Activity UDP-glycosyltransferase Activity Leukocyte Tethering Or Rolling Golgi Lumen Leukocyte Adhesion To Vascular Endothelial Cell Viral Protein Processing Basement Membrane Organization Bone Morphogenesis Lymphocyte Adhesion To Endothelial Cell Of High Endothelial Venule Perichondral Bone Morphogenesis Sweat Gland Development Smoothened Signaling Pathway Involved In Lung Development Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Peptidyl-tyrosine Sulfation Perforant Pathway To Dendrate Granule Cell Synapse Golgi Stack N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase Activity Mesenchymal Cell Differentiation Involved In Bone Development Stomach Development Heparan Sulfate N-acetylglucosaminyltransferase Activity Trans-Golgi Network Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity	Membrane Protein Binding Protein Targeting To Golgi Apparatus Golgi Vesicle Budding Cargo Adaptor Activity
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