B4GALT4

Name	beta-1,4-galactosyltransferase 4
Structure	No pdb structure
Novel Interactors	2 novel interactors: POLE4 TIGIT
Interactors	2 interactors: GOLPH3 GOLPH3L
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Golgi Apparatus Membrane
	Molecular Function	N-acetyllactosamine Synthase Activity Protein Binding Galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity UDP-galactosyltransferase Activity Metal Ion Binding
	Biological Process	Lactosylceramide Biosynthetic Process Carbohydrate Metabolic Process Protein Glycosylation Lipid Metabolic Process Membrane Lipid Metabolic Process Keratan Sulfate Proteoglycan Biosynthetic Process Glycosylation
Pathways	Keratan sulfate biosynthesis N-Glycan antennae elongation
Drugs	N-Acetylglucosamine
GWAS	Clozapine-induced cytotoxicity ( 25656473 ) First year height change in growth hormone-treated short stature ( 32652002 ) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042 ) Survival in pancreatic cancer ( 28470677 )
Entrez ID	8702
HPRD ID	04930
Ensembl ID	ENSG00000121578
Uniprot IDs	B2RAZ5 B3KM35 E7ETS9 O60513
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Asymmetric Golgi Ribbon Formation Protein Localization To Plasma Membrane Trans-Golgi Network Cell Adhesion Molecule Production Cellular Response To Rapamycin Protein Targeting Establishment Of Protein Localization To Membrane Protein Retention In Golgi Apparatus Protein Localization To Cell Periphery Epsilon DNA Polymerase Complex Positive Regulation Of Protein Transport Regulation Of Protein Secretion Response To Rapamycin Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Protein Localization To Membrane Lipid Binding Establishment Of Protein Localization To Organelle Golgi Ribbon Formation Cellular Response To Ether ATAC Complex Regulation Of Protein Transport Positive Regulation Of Protein Localization Negative Regulation Of Interleukin-12 Production Leukocyte Tethering Or Rolling DNA-directed DNA Polymerase Activity Response To Ether Localization Within Membrane Regulation Of Establishment Of Protein Localization Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Secretion By Cell