GOLPH3L and MGAT2

Number of citations of the paper that reports this interaction (PubMedID 34473204)
68

Data Source:
BioGRID (pull down)

		GOLPH3L	MGAT2
Description		golgi phosphoprotein 3 like	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Golgi Cisterna Golgi Cisterna Membrane Trans-Golgi Network Membrane	Golgi Membrane Golgi Apparatus Golgi Stack Membrane
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-4-phosphate Binding Cargo Adaptor Activity	Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Manganese Ion Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Golgi To Plasma Membrane Protein Transport Golgi Vesicle Budding Positive Regulation Of Protein Secretion Protein Targeting To Golgi Apparatus	Protein Glycosylation Protein N-linked Glycosylation Oligosaccharide Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Viral Protein Processing
Pathways			Defective MGAT2 causes CDG-2a Maturation of spike protein Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Basal cell carcinoma ( 31174203) Body mass index ( 26426971) Caffeine consumption from coffee ( 33287642) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Chronotype ( 30696823) Keratinocyte cancer (MTAG) ( 31174203) Morning person ( 30696823) Neutrophil percentage of white cells ( 27863252) Prostate cancer ( 25217961) Refractive error ( 32231278) Rhegmatogenous retinal detachment ( 23585552) Triglyceride levels ( 32203549) Urate levels ( 31578528)	Blood protein levels ( 30072576)
Interacting Genes		26 interacting genes: ARL6IP1 B4GALT4 C1GALT1 CANT1 DIPK2A EBAG9 EXT1 FAM20B FAM3C GALNT2 GALNT6 GALNT7 GCNT1 GLG1 GLT8D1 GOLIM4 GOLM2 HTT LNX1 MAN1B1 MGAT2 PGAP4 POMGNT1 TPST1 TPST2 ZDHHC17	2 interacting genes: GOLPH3 GOLPH3L
Entrez ID		55204	4247
HPRD ID		17048	04013
Ensembl ID		ENSG00000143457	ENSG00000168282
Uniprot IDs		Q9H4A5	Q10469
PDB IDs			5VCM 5VCR 5VCS
Enriched GO Terms of Interacting Partners?		Golgi Apparatus Golgi Membrane Glycoprotein Metabolic Process Glycosyltransferase Activity Glycoprotein Biosynthetic Process Protein Glycosylation Macromolecule Glycosylation Glycosylation Carbohydrate Derivative Metabolic Process Carbohydrate Derivative Biosynthetic Process Protein O-linked Glycosylation Transferase Activity Protein O-linked Glycosylation Via N-acetyl-galactosamine Protein Modification Process Protein Metabolic Process Macromolecule Biosynthetic Process Polypeptide N-acetylgalactosaminyltransferase Activity Membrane Proteoglycan Biosynthetic Process Protein-tyrosine Sulfotransferase Activity Carbohydrate Binding Proteoglycan Metabolic Process Macromolecule Metabolic Process Manganese Ion Binding Golgi Cisterna Membrane 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Carbohydrate Metabolic Process Sulfation Acetylglucosaminyltransferase Activity UDP-glycosyltransferase Activity Leukocyte Tethering Or Rolling Golgi Lumen Leukocyte Adhesion To Vascular Endothelial Cell Viral Protein Processing Basement Membrane Organization Bone Morphogenesis Lymphocyte Adhesion To Endothelial Cell Of High Endothelial Venule Perichondral Bone Morphogenesis Sweat Gland Development Smoothened Signaling Pathway Involved In Lung Development Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Peptidyl-tyrosine Sulfation Perforant Pathway To Dendrate Granule Cell Synapse Golgi Stack N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase Activity Mesenchymal Cell Differentiation Involved In Bone Development Stomach Development Heparan Sulfate N-acetylglucosaminyltransferase Activity Trans-Golgi Network Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity	Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Protein Targeting Establishment Of Protein Localization To Membrane Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Establishment Of Protein Localization To Organelle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Localization Within Membrane Mitochondrial Intermembrane Space Membrane Organization Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Asymmetric Golgi Ribbon Formation Trans-Golgi Network Cell Adhesion Molecule Production Cellular Response To Rapamycin Detection Of Nodal Flow Protein Localization To Plasma Membrane Protein Transport Protein Retention In Golgi Apparatus Protein Localization To Cell Periphery Positive Regulation Of Protein Transport Mitochondrial Intermembrane Space Chaperone Complex Regulation Of Protein Secretion Response To Rapamycin Establishment Of Protein Localization Golgi Vesicle Transport TIM22 Mitochondrial Import Inner Membrane Insertion Complex Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Protein Localization To Membrane Lipid Binding Golgi Ribbon Formation Cellular Localization Cellular Response To Ether Left/right Axis Specification Protein Transporter Activity Membrane Insertase Activity Regulation Of Protein Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?