MAP1S and RASSF5

Number of citations of the paper that reports this interaction (PMID 20562859)
242

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		MAP1S	RASSF5
Gene Name		microtubule-associated protein 1S	Ras association (RalGDS/AF-6) domain family member 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Spindle Cytosol Microtubule Cell Junction Dendrite Cell Projection Neuronal Cell Body Synapse Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Microtubule
	Molecular Function	DNA Binding Deoxyribonuclease Activity Protein Binding Microtubule Binding Tubulin Binding Identical Protein Binding Beta-tubulin Binding Actin Filament Binding	Protein Binding Metal Ion Binding
	Biological Process	Microtubule Bundle Formation Apoptotic DNA Fragmentation Nervous System Development Brain Development Mitochondrion Transport Along Microtubule Neuron Projection Morphogenesis Execution Phase Of Apoptosis	Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		10 interactors: BPY2 BPY2C HDAC4 LRPPRC MAP1LC3A PIN1 RASSF1 RASSF5 SLC2A4 SOCS3	31 interactors: ADH6 AMOTL2 APPBP2 BTRC HRAS KRAS KRT40 KRTAP4-2 LSM7 MAP1S MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK3 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 VPS28
Entrez ID		55201	83593
HPRD ID		10461	06117
Ensembl ID		ENSG00000130479	ENSG00000136653
Uniprot IDs		B4DH53 Q66K74	Q8WWW0
PDB IDs			4LGD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Ubiquitination Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Amylopectin Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process Response To Stress Positive Regulation Of Protein Metabolic Process Single Fertilization Spongiotrophoblast Differentiation Fertilization Response To Cytokine Negative Regulation Of Glycolytic Process Peptidyl-lysine Deacetylation Response To Denervation Involved In Regulation Of Muscle Adaptation Glucose Import	Ras Protein Signal Transduction Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Signal Transduction Positive Regulation Of Rac Protein Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Phosphorylation Regulation Of Intracellular Signal Transduction Signaling Cell Communication Regulation Of Signaling Response To Stimulus Branching Morphogenesis Of An Epithelial Tube Regulation Of Phosphorylation Rap Protein Signal Transduction Positive Regulation Of Transferase Activity Regulation Of Protein Phosphorylation Epithelial Tube Morphogenesis Morphogenesis Of A Branching Epithelium Regulation Of MAPK Cascade Morphogenesis Of A Branching Structure Regulation Of Phosphorus Metabolic Process Tube Morphogenesis Endocardium Development Regulation Of Cell Death Positive Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Regulation Of Neuron Death Positive Regulation Of Kinase Activity Regulation Of Protein Kinase Activity Morphogenesis Of An Epithelium Positive Regulation Of Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Neuron Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Hippo Signaling Neurotrophin Signaling Pathway Regulation Of Long-term Neuronal Synaptic Plasticity Tissue Morphogenesis Regulation Of Synaptic Transmission, GABAergic
Tagcloud ?		adenocarcinomas autophagic autophagosomal autophagy biogenesis bridges c19orf5 collaboration collaboratively diethylnitrosamine guangzhou h2ax hepatocelular immunochemical inc lrpprc map1a map1b microtubules mitochondrion named originally p62 pca periodicals survive vary wildtype wiley	action activates acts allows arrest catenin dictate effector exhibit explanation frequently ikappab ligase lost nore1a observation oncogene promoted promoting proteasome scf stimulate substrate suppressor toward trcp ubiquitin wnt
Tagcloud (Difference) ?		adenocarcinomas autophagic autophagosomal autophagy biogenesis bridges c19orf5 collaboration collaboratively diethylnitrosamine guangzhou h2ax hepatocelular immunochemical inc lrpprc map1a map1b microtubules mitochondrion named originally p62 pca periodicals survive vary wildtype wiley	action activates acts allows arrest catenin dictate effector exhibit explanation frequently ikappab ligase lost nore1a observation oncogene promoted promoting proteasome scf stimulate substrate suppressor toward trcp ubiquitin wnt
Tagcloud (Intersection) ?