SH3GLB1 and CACFD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SH3GLB1	CACFD1
Description		SH3 domain containing GRB2 like, endophilin B1	calcium channel flower domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Golgi Apparatus Cytosol Membrane Nuclear Body Midbody Cytoplasmic Vesicle Protein-containing Complex	Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Synapse Recycling Endosome
	Molecular Function	Fatty Acid Binding Protein Binding Lipid Binding Lysophosphatidic Acid Acyltransferase Activity Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Phosphatidylinositol 3-kinase Activator Activity	Protein Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Autophagy Apoptotic Process Phospholipid Biosynthetic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein-containing Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death 'de Novo' Post-translational Protein Folding Membrane Organization Membrane Fission Positive Regulation Of Membrane Tubulation Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly	Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS			Gut microbiota (functional units) ( 27694959)
Interacting Genes		52 interacting genes: ABHD5 ADAM15 ADAM9 AGTRAP AMPH APP ARFIP2 ARHGAP17 BAX BIN1 C1D CACFD1 CDKN2D CMTM5 COQ8A DESI2 DNM2 EXOSC5 F8A1 FAM114A2 FN1 FUNDC1 GADD45A GADD45G GSTP1 HTATIP2 HTT IRGM ITGB1BP2 MAL2 MTA1 PSMA1 RABAC1 RABGGTB RHEX RIC8A SH3GLB2 SH3KBP1 SIN3A SMIM5 SNX1 SNX4 SYNGR3 SYNJ1 SYP TAX1BP1 TFIP11 TPD52 TPD52L2 TTN UBL7 ZNF576	11 interacting genes: CREB3 HSFX1 HSFX2 LDAF1 MTERF3 NDRG4 PITPNC1 PNKP RBFA SH3GLB1 SNCA
Entrez ID		51100	11094
HPRD ID		15333	12974
Ensembl ID		ENSG00000097033	ENSG00000160325
Uniprot IDs		A0A087WW40 A0A140VJU5 A0A994J549 Q9Y371	Q9UGQ2
PDB IDs		6UP6 6UPN 9G2R 9G2U 9G2W
Enriched GO Terms of Interacting Partners?		Cytoplasmic Vesicle Protein Binding SH3 Domain Binding Synaptic Vesicle Vesicle-mediated Transport Insulin Receptor Binding Leptin Receptor Binding Endocytosis Integrin Binding BH3 Domain Binding Cytoplasm Synaptic Vesicle Transport Synaptic Vesicle Endocytosis Presynaptic Endocytosis Positive Regulation Of Programmed Cell Death Peptidase Activator Activity Positive Regulation Of Catabolic Process Establishment Of Vesicle Localization	Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Mitochondrial Outer Membrane Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Fatty Acid Binding Positive Regulation Of Deacetylase Activity Protein Localization To Vacuolar Membrane
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