SH3GLB1 and TPD52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SH3GLB1	TPD52
Description		SH3 domain containing GRB2 like, endophilin B1	tumor protein D52
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Golgi Apparatus Cytosol Membrane Nuclear Body Midbody Cytoplasmic Vesicle Protein-containing Complex	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Fatty Acid Binding Protein Binding Lipid Binding Lysophosphatidic Acid Acyltransferase Activity Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Phosphatidylinositol 3-kinase Activator Activity	Calcium Ion Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Phosphatidic Acid Biosynthetic Process Autophagy Apoptotic Process Phospholipid Biosynthetic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein-containing Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death 'de Novo' Post-translational Protein Folding Membrane Organization Membrane Fission Positive Regulation Of Membrane Tubulation Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly	Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis B Cell Differentiation Secretion
Pathways			Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 34103634 31959851 31619474 31361310 29273806 27182965) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Kawasaki disease ( 33772158) Lapatinib-induced hepatotoxicity ( 25987243) Metabolite levels (HVA/MHPG ratio) ( 23319000) Metabolite levels (Pyroglutamine) ( 23934736) Rheumatoid arthritis ( 30423114 24390342) Self-reported allergy ( 23817569)
Interacting Genes		52 interacting genes: ABHD5 ADAM15 ADAM9 AGTRAP AMPH APP ARFIP2 ARHGAP17 BAX BIN1 C1D CACFD1 CDKN2D CMTM5 COQ8A DESI2 DNM2 EXOSC5 F8A1 FAM114A2 FN1 FUNDC1 GADD45A GADD45G GSTP1 HTATIP2 HTT IRGM ITGB1BP2 MAL2 MTA1 PSMA1 RABAC1 RABGGTB RHEX RIC8A SH3GLB2 SH3KBP1 SIN3A SMIM5 SNX1 SNX4 SYNGR3 SYNJ1 SYP TAX1BP1 TFIP11 TPD52 TPD52L2 TTN UBL7 ZNF576	17 interacting genes: ANXA6 AR MAL2 MAPK3 SENP2 SH3GLB1 SOCS2 SPG21 SPOP SRPK2 STUB1 THAP4 TPD52L1 TPD52L2 TPD52L3 TTPA UBC
Entrez ID		51100	7163
HPRD ID		15333	04963
Ensembl ID		ENSG00000097033	ENSG00000076554
Uniprot IDs		A0A087WW40 A0A140VJU5 A0A994J549 Q9Y371	P55327
PDB IDs		6UP6 6UPN 9G2R 9G2U 9G2W
Enriched GO Terms of Interacting Partners?		Cytoplasmic Vesicle Protein Binding SH3 Domain Binding Synaptic Vesicle Vesicle-mediated Transport Insulin Receptor Binding Leptin Receptor Binding Endocytosis Integrin Binding BH3 Domain Binding Cytoplasm Synaptic Vesicle Transport Synaptic Vesicle Endocytosis Presynaptic Endocytosis Positive Regulation Of Programmed Cell Death Peptidase Activator Activity Positive Regulation Of Catabolic Process Establishment Of Vesicle Localization	Cytoplasm Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ERBB Signaling Pathway Mammary Gland Alveolus Development Positive Regulation Of Macroautophagy Animal Organ Formation ERBB2 Signaling Pathway Lipid Binding Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Protein Stability Protein Modification By Small Protein Conjugation Insulin-like Growth Factor Receptor Signaling Pathway Prostate Induction Male Somatic Sex Determination Protein Modification Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Negative Regulation Of Establishment Of Blood-brain Barrier Post-translational Protein Modification Positive Regulation Of Chaperone-mediated Protein Complex Assembly Peroxynitrite Isomerase Activity Protein Localization To Vacuolar Membrane Response To Epidermal Growth Factor
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