PPP1R7 and MYH3

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		PPP1R7	MYH3
Description		protein phosphatase 1 regulatory subunit 7	myosin heavy chain 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm Extracellular Exosome	Cytoplasm Cytosol Muscle Myosin Complex Myosin Complex Myosin II Complex Myofibril Sarcomere Myosin Filament Contractile Muscle Fiber Extracellular Exosome
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Enzyme Regulator Activity	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Calmodulin Binding ATP Binding ATP Hydrolysis Activity Myosin Phosphatase Activity Actin Filament Binding
	Biological Process		Skeletal Muscle Contraction Muscle Contraction Muscle Organ Development Actin Filament-based Movement Muscle Filament Sliding Embryonic Limb Morphogenesis Sarcomere Organization ATP Metabolic Process Face Morphogenesis
Pathways			Striated Muscle Contraction
Drugs
Diseases			Distal arthrogryposis (DA)
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847)	Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Relative hand skill in reading disability ( 24068947)
Interacting Genes		16 interacting genes: CLNK FER HGS MAPK6 MYH3 OGT PPP1CB PPP1CC PPP1R3A SPRED1 TAB1 TNFRSF6B UBC UBXN2B USHBP1 VCP	9 interacting genes: APPL1 CLIP4 DYSF LAMTOR5 OPTN PPP1R7 PRKD3 SNAPIN TULP3
Entrez ID		5510	4621
HPRD ID		04192	01172
Ensembl ID		ENSG00000115685	ENSG00000109063
Uniprot IDs		A0A140VK83 Q15435	P11055 Q5GJ67
PDB IDs		6HKW 6MKY 6OBN 6OBP 8B5R 8U5G
Enriched GO Terms of Interacting Partners?		Protein Phosphatase 1 Binding Protein-containing Complex Myosin Phosphatase Activity Glycogen Metabolic Process PTW/PP1 Phosphatase Complex Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Polysaccharide Metabolic Process Protein Serine/threonine Phosphatase Activity Intracellular Signal Transduction Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Protein-containing Complex Binding Regulation Of Generation Of Precursor Metabolites And Energy Ubiquitin-like Protein Ligase Binding Photoperiodism Entrainment Of Circadian Clock Protein Modification Process Protein Exit From Endoplasmic Reticulum Cytosol Macroautophagy Protein Kinase Binding Energy Derivation By Oxidation Of Organic Compounds Endosome Transport Via Multivesicular Body Sorting Pathway Adherens Junction Disassembly Intracellular Signaling Cassette Myosin-light-chain-phosphatase Activity Flavin Adenine Dinucleotide Catabolic Process Multivesicular Body Sorting Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Phosphate-containing Compound Metabolic Process Protein Domain Specific Binding Cytoplasm MAPK Cascade Protein Localization To Lysosome Canonical NF-kappaB Signal Transduction Regulation Of Phosphorus Metabolic Process Cell-cell Junction Disassembly Rhythmic Process Septin Cytoskeleton VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Positive Regulation Of Protein K63-linked Deubiquitination Negative Regulation Of Protein Localization To Centrosome Regulation Of Protein Modification Process Kit Signaling Pathway Protein Metabolic Process Phosphatase Activity Regulation Of ATP Metabolic Process	Negative Regulation Of Phagocytosis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?