MYH3 and TULP3

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		MYH3	TULP3
Description		myosin heavy chain 3	TUB like protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Muscle Myosin Complex Myosin Complex Myosin II Complex Myofibril Sarcomere Myosin Filament Contractile Muscle Fiber Extracellular Exosome	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cilium Axoneme Membrane Ciliary Basal Body Cell Projection Ciliary Base 9+0 Non-motile Cilium
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Calmodulin Binding ATP Binding ATP Hydrolysis Activity Myosin Phosphatase Activity Actin Filament Binding	G Protein-coupled Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Enzyme Binding Phosphatidylinositol Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Muscle Organ Development Actin Filament-based Movement Muscle Filament Sliding Embryonic Limb Morphogenesis Sarcomere Organization ATP Metabolic Process Face Morphogenesis	Neural Tube Formation Neural Tube Closure Regulation Of DNA-templated Transcription G Protein-coupled Receptor Signaling Pathway Smoothened Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Smoothened Signaling Pathway Anterior/posterior Pattern Specification Dorsal/ventral Neural Tube Patterning Neural Tube Development Central Nervous System Neuron Differentiation Embryonic Camera-type Eye Development Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Limb Development Bone Development Bronchus Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Ganglion Development
Pathways		Striated Muscle Contraction	Hedgehog 'off' state
Drugs
Diseases		Distal arthrogryposis (DA)
GWAS		Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Relative hand skill in reading disability ( 24068947)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		9 interacting genes: APPL1 CLIP4 DYSF LAMTOR5 OPTN PPP1R7 PRKD3 SNAPIN TULP3	61 interacting genes: ACTN2 AKAP9 ANKRD1 ARHGAP21 ARMCX2 ATP2A1 BACH2 BOC BRMS1L BTBD1 CCNB1 CHD2 CLIP4 DNTTIP2 DROSHA DST ESRRG GPATCH2L GSE1 HSF2BP KIF3A KLF10 KRTAP10-1 KRTAP10-5 KRTAP10-7 MAGEA6 MAP3K5 MBTD1 MGA MORF4L1 MYBPC2 MYH3 MYH7 MYO18B NCOR1 NFE2L1 NOSTRIN NRIP1 PAF1 PCGF6 PDE4DIP PHAX PSTPIP1 RCOR3 RIOK3 RNF10 ROPN1 RYR1 SLAIN2 SPTB SRP72 TNNT1 TNNT3 WNK1 ZFAT ZNF160 ZNF462 ZNF619 ZNF793 ZNF835 ZSCAN23
Entrez ID		4621	7289
HPRD ID		01172	05292
Ensembl ID		ENSG00000109063	ENSG00000078246
Uniprot IDs		P11055 Q5GJ67	B7Z1E7 O75386
PDB IDs			8FH3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phagocytosis	Sarcomere Organization Actomyosin Structure Organization Cytoskeleton Organization Regulation Of RNA Metabolic Process Myosin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Skeletal Muscle Contraction Actin Filament-based Process H Zone Striated Muscle Contraction Myofibril Actin Cytoskeleton Organization Sarcomere Actin Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Microtubule Plus-end Myosin II Complex Organelle Organization I Band Histone Deacetylase Binding Z Disc Extrinsic Component Of Postsynaptic Density Membrane Striated Muscle Cell Development Regulation Of Macromolecule Biosynthetic Process Microtubule Cytoskeleton Organization Positive Regulation Of Microtubule Polymerization DNA Binding Transition Between Fast And Slow Fiber Muscle System Process Negative Regulation Of RNA Metabolic Process Troponin Complex Cardiac Muscle Cell Development Muscle Cell Development Nucleus Positive Regulation Of RNA Metabolic Process Histone Deacetylase Complex Regulation Of Primary Metabolic Process Cardiac Cell Development Microtubule-based Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Skeletal Muscle Adaptation Myosin Complex Actin Filament Binding
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