C14orf119 and CDC14A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C14orf119	CDC14A
Description		chromosome 14 open reading frame 119	cell division cycle 14A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Centrosome Microtubule Organizing Center Spindle Cytosol Cytoskeleton Stereocilium Stereocilium Tip Cell Projection Kinocilium Mitotic Spindle Kinociliary Basal Body
	Molecular Function	Protein Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity
	Biological Process		Microtubule Cytoskeleton Organization Regulation Of Exit From Mitosis Sensory Perception Of Sound Positive Regulation Of Cytokinesis Cell Division Cilium Assembly
Pathways			Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS			Estimated glomerular filtration rate ( 31015462 31152163) Fasting glucose ( 34059833) Fever and diarrhea in mesalamine-treated irritable bowel disease ( 33501934) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009)
Interacting Genes		56 interacting genes: ACTN4 ARID3C ARID5A AUNIP BEND7 BIN3 C1QTNF1 CCND3 CDC14A CHMP1A CLPP CTAG1A CTAG1B DDIT4L DECR2 DYNLL1 DYNLL2 HES6 HLX HMG20B ITGB3BP KHDC4 KRT4 KRT78 KRTAP13-3 LASP1 LDB2 LENG1 LRRCC1 MEOX1 MORN3 MYF5 NIF3L1 NME4 NRIP3 NUP54 NUP62 PBX4 PHACTR1 PINX1 RAB3IL1 REL RHOU RND3 RNF4 RPIA SMCP SNX8 SSX4 SSX4B STN1 SYCP3 TEX35 TLE5 UBXN11 WASHC1	16 interacting genes: AATK ATPAF2 BRAP C14orf119 CDC25B CDC6 CHRM1 FZR1 KIF20A LMTK2 PLK1 POLR2A PTK7 ROR2 TP53 WEE1
Entrez ID		55017	8556
HPRD ID		16595	04614
Ensembl ID		ENSG00000179933	ENSG00000079335
Uniprot IDs		Q9NWQ9	A0A0U1RQX7 B4DY86 Q59EF4 Q9UNH5
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Regulation Of Cell Cycle G2/M Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cytokinesis Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Process Protein Kinase Activity ATP Binding Negative Regulation Of Cell Cycle Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic G2/M Transition Checkpoint Regulation Of Cell Division Cell Cycle G2/M Phase Transition Regulation Of Cell Cycle Anaphase-promoting Complex Binding Mitotic DNA Damage Checkpoint Signaling Cell Division Mitotic Nuclear Membrane Disassembly Positive Regulation Of Ubiquitin-protein Transferase Activity Nuclear Membrane Disassembly Positive Regulation Of Mitotic Cell Cycle Phase Transition Membrane Disassembly DNA Damage Checkpoint Signaling Positive Regulation Of Cell Cycle Phase Transition Regulation Of DNA Replication Kinase Activity Positive Regulation Of Mitotic Cell Cycle Protein Tyrosine Kinase Activity Negative Regulation Of DNA Replication Negative Regulation Of DNA Metabolic Process Spindle Midzone Regulation Of Ubiquitin-protein Transferase Activity Mitotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Spindle Pole Positive Regulation Of Cell Cycle G2/M Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition
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