PRPF39 and TRNAU1AP

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid)

		PRPF39	TRNAU1AP
Description		pre-mRNA processing factor 39	tRNA selenocysteine 1 associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Commitment Complex Nucleus U1 SnRNP U2-type Prespliceosome	Nucleus Cytoplasm
	Molecular Function	Protein Binding Pre-mRNA 5'-splice Site Binding	TRNA Binding Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	MRNA 5'-splice Site Recognition RNA Processing MRNA Processing RNA Splicing	Selenocysteine Incorporation Translation
Pathways
Drugs
Diseases
GWAS		Lead levels ( 26025379)
Interacting Genes		14 interacting genes: BANP CEBPA DHX30 DMRTB1 GTSE1 LARP4 MBNL1 PRRC2B QKI RBM22 RNU1-1 SF1 TOLLIP TRNAU1AP	9 interacting genes: BCAS2 DMRTB1 GTSE1 PRPF39 PRRC2B QKI RBM42 SECISBP2 USP10
Entrez ID		55015	54952
HPRD ID		17913	18035
Ensembl ID		ENSG00000185246	ENSG00000180098
Uniprot IDs		Q86UA1	Q9NX07
PDB IDs			2DHG 2DIV
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding Protein Localization To Endosome Cytoplasmic Stress Granule MRNA Cis Splicing, Via Spliceosome RNA Splicing Erythrocyte Apoptotic Process Macrophage Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Internal N(7)-methylguanine-containing RNA Reader Activity	RNA Splicing Negative Regulation Of MRNA Metabolic Process MRNA Processing Stress Granule Assembly Nucleic Acid Metabolic Process RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process MRNA Splicing, Via Spliceosome DNA Damage Response, Signal Transduction By P53 Class Mediator Membraneless Organelle Assembly RNA Metabolic Process Translational Elongation RNA Binding Regulation Of MRNA Metabolic Process MRNA Stabilization Internal N(7)-methylguanine-containing RNA Reader Activity Nucleobase-containing Compound Metabolic Process RNA Processing Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Stress Granule Assembly Myofibroblast Contraction Negative Regulation Of RNA Catabolic Process Negative Regulation Of MiRNA Catabolic Process Signal Transduction By P53 Class Mediator Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA 3'-UTR Binding Spliceosome-depend Formation Of Circular RNA Pre-mRNA 5'-splice Site Binding Selenocysteine Insertion Sequence Binding Commitment Complex Signal Transduction In Response To DNA Damage Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of RNA Splicing Regulation Of MRNA Stability Germ Cell Development Microglia Differentiation Negative Regulation Of Macrophage Differentiation Spliceosomal Complex MRNA 5'-splice Site Recognition Selenocysteine Incorporation Monoubiquitinated Protein Deubiquitination Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Vascular Associated Smooth Muscle Cell Differentiation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Organelle Assembly Regulation Of RNA Stability Regulation Of Stress Granule Assembly Intracellular MRNA Localization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?