PRPF39 and RNU1-1

Number of citations of the paper that reports this interaction (PubMedID 29051543)
77

Data Source:
BioGRID (unspecified method)

		PRPF39	RNU1-1
Description		pre-mRNA processing factor 39	RNA, U1 small nuclear 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Commitment Complex Nucleus U1 SnRNP U2-type Prespliceosome
	Molecular Function	Protein Binding Pre-mRNA 5'-splice Site Binding
	Biological Process	MRNA 5'-splice Site Recognition RNA Processing MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Lead levels ( 26025379)
Interacting Genes		14 interacting genes: BANP CEBPA DHX30 DMRTB1 GTSE1 LARP4 MBNL1 PRRC2B QKI RBM22 RNU1-1 SF1 TOLLIP TRNAU1AP	12 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 PRPF39 RAE1 SMN1 SND1 STRAP
Entrez ID		55015	26871
HPRD ID		17913
Ensembl ID		ENSG00000185246	ENSG00000206652
Uniprot IDs		Q86UA1
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding Protein Localization To Endosome Cytoplasmic Stress Granule MRNA Cis Splicing, Via Spliceosome RNA Splicing Erythrocyte Apoptotic Process Macrophage Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Internal N(7)-methylguanine-containing RNA Reader Activity	SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly MRNA Metabolic Process RNA Splicing MRNA Processing RNA Processing RNA Metabolic Process Protein-containing Complex Assembly Nucleic Acid Metabolic Process Protein-containing Complex Organization Nuclear Body RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Cellular Component Assembly Spliceosomal Complex Assembly Nucleus Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome RNA Binding Nucleoplasm Cytosol Cytoplasm SMN-Gemin2 Complex RNAi Effector Complex Sm-like Protein Family Complex Cajal Body U2 SnRNP Binding U4atac SnRNA Binding Pre-mRNA 5'-splice Site Binding RISC Complex Binding Dense Body Commitment Complex Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding MRNA 5'-splice Site Recognition SnRNA Binding MiRNA Catabolic Process Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding
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