FAM118A and WDR4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM118A	WDR4
Gene Name		family with sequence similarity 118, member A	WD repeat domain 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function		Protein Binding TRNA (guanine-N7-)-methyltransferase Activity
	Biological Process		TRNA Modification TRNA Methylation RNA (guanine-N7)-methylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AIDA ATOX1 FAM118B GLRX3 LNX1 MOB1A MOB3C SDCBP WDR4	5 interactors: FAM118A METTL1 RABGGTB TERF1 TERF2
Entrez ID		55007	10785
HPRD ID		07936	09330
Ensembl ID		ENSG00000100376	ENSG00000160193
Uniprot IDs		Q9NWS6	P57081
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Copper Ion Transport Regulation Of JNK Cascade Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Stress-activated MAPK Cascade RNA (guanine-N7)-methylation Regulation Of Extracellular Vesicular Exosome Assembly	Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Replicative Cell Aging Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Cell Aging Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Regulation Of DNA Replication Regulation Of Chromosome Organization RNA (guanine-N7)-methylation Protection From Non-homologous End Joining At Telomere Telomere Capping DNA Replication Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Protein Geranylgeranylation Aging Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cell Cycle Positive Regulation Of Microtubule Polymerization Regulation Of Cell Cycle Process Regulation Of Telomerase Activity Protein Prenylation Chromatin Modification TRNA Methylation Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Protein Localization To Chromosome Cellular Senescence Chromatin Organization 7-methylguanosine RNA Capping Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint
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