MNDA and PRMT7

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		MNDA	PRMT7
Gene Name		myeloid cell nuclear differentiation antigen	protein arginine methyltransferase 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane
	Molecular Function	DNA Binding Protein Binding	Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Defense Response Cellular Response To DNA Damage Stimulus Negative Regulation Of B Cell Proliferation Positive Regulation Of Apoptotic Process B Cell Receptor Signaling Pathway	Spliceosomal SnRNP Assembly Chromatin Organization Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Magnesium levels ( 20700443)
Protein-Protein Interactions		9 interactors: CDK1 CDK2 HOXB2 PRMT6 PRMT7 RB1 RBL2 TP53 WHSC1L1	10 interactors: CTCFL DIO3 H3F3C HIST1H3A HIST1H4A HIST2H2AC MNDA POT1 SNRPB ZBTB24
Entrez ID		4332	54496
HPRD ID		15932	15174
Ensembl ID		ENSG00000163563	ENSG00000132600
Uniprot IDs		P41218 Q5VUU6	Q9NVM4
PDB IDs		2DBG
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromosome Organization Chromatin Modification Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Regulation Of Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organelle Organization Negative Regulation Of Mitotic Cell Cycle Ras Protein Signal Transduction Cellular Nitrogen Compound Metabolic Process Cell Cycle Checkpoint Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Transcription, DNA-templated Glial Cell Apoptotic Process RNA Biosynthetic Process Mitotic Cell Cycle Histone H4-R3 Methylation Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Protein Localization To Chromosome, Centromeric Region Peptidyl-arginine N-methylation Regulation Of Cell Cycle Histone Methylation Regulation Of Mitotic Cell Cycle Regulation Of DNA Replication Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Histone Arginine Methylation DNA Metabolic Process Peptidyl-arginine Methylation DNA Damage Checkpoint RNA Metabolic Process G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle	DNA Methylation DNA Modification DNA Replication-dependent Nucleosome Assembly DNA Methylation On Cytosine Chromatin Silencing At RDNA Regulation Of Gene Expression, Epigenetic Cellular Aromatic Compound Metabolic Process Chromatin Silencing Cellular Nitrogen Compound Metabolic Process DNA Conformation Change Nitrogen Compound Metabolic Process Telomere Maintenance Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of DNA Strand Elongation Chromosome Organization Methylation DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Silencing Thyroid Hormone Catabolic Process Heterocycle Metabolic Process Nucleosome Assembly Gene Expression Telomere Formation Via Telomerase Histone H4-K20 Demethylation Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Cellular Macromolecular Complex Assembly Negative Regulation Of Megakaryocyte Differentiation Protein-DNA Complex Assembly Positive Regulation Of Helicase Activity Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase DNA Packaging Chromatin Organization Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Hormone Catabolic Process Regulation Of Chromosome Organization Positive Regulation Of Growth Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Cellular Component Assembly Regulation Of Telomerase Activity
Tagcloud ?		adds capabilities cg challenging comparability confirming cytogenetics cytomorphology cytopenic details diagnostics dimg dimm discriminating dyspoiesis giving grades granulocytes investigator mfc mfi monocytes multiparameter myelomonocytic outlined panels percentages upcoming weakly
Tagcloud (Difference) ?		adds capabilities cg challenging comparability confirming cytogenetics cytomorphology cytopenic details diagnostics dimg dimm discriminating dyspoiesis giving grades granulocytes investigator mfc mfi monocytes multiparameter myelomonocytic outlined panels percentages upcoming weakly
Tagcloud (Intersection) ?