MNDA and WHSC1L1

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		MNDA	WHSC1L1
Gene Name		myeloid cell nuclear differentiation antigen	Wolf-Hirschhorn syndrome candidate 1-like 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Chromosome
	Molecular Function	DNA Binding Protein Binding	Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K4 Specific) Histone Methyltransferase Activity (H3-K27 Specific)
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Defense Response Cellular Response To DNA Damage Stimulus Negative Regulation Of B Cell Proliferation Positive Regulation Of Apoptotic Process B Cell Receptor Signaling Pathway	Chromatin Organization Transcription, DNA-templated Histone Methylation Negative Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation Histone H3-K27 Methylation
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Schizophrenia ( 22037555)
Protein-Protein Interactions		9 interactors: CDK1 CDK2 HOXB2 PRMT6 PRMT7 RB1 RBL2 TP53 WHSC1L1	17 interactors: CBX3 CBX5 DAXX DOCK7 ETV3 GLYR1 H3F3C HIST1H1A HOXC4 MLLT6 MNDA SEPT6 SLU7 SPAG8 STAC3 UBE2I ZNF557
Entrez ID		4332	54904
HPRD ID		15932	06155
Ensembl ID		ENSG00000163563	ENSG00000147548
Uniprot IDs		P41218 Q5VUU6	B7ZL11 Q9BZ95
PDB IDs		2DBG	2DAQ 4GND 4GNE 4GNF 4GNG
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromosome Organization Chromatin Modification Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Regulation Of Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Organelle Organization Negative Regulation Of Mitotic Cell Cycle Ras Protein Signal Transduction Cellular Nitrogen Compound Metabolic Process Cell Cycle Checkpoint Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Transcription, DNA-templated Glial Cell Apoptotic Process RNA Biosynthetic Process Mitotic Cell Cycle Histone H4-R3 Methylation Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Protein Localization To Chromosome, Centromeric Region Peptidyl-arginine N-methylation Regulation Of Cell Cycle Histone Methylation Regulation Of Mitotic Cell Cycle Regulation Of DNA Replication Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Histone Arginine Methylation DNA Metabolic Process Peptidyl-arginine Methylation DNA Damage Checkpoint RNA Metabolic Process G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle	Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cell Division Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Establishment Of Neuroblast Polarity Cytokinesis Nucleosome Assembly MRNA 3'-splice Site Recognition Transcription, DNA-templated Chromatin Assembly RNA Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Gene Expression Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Remodeling DNA Packaging Nucleobase-containing Compound Metabolic Process
Tagcloud ?		adds capabilities cg challenging comparability confirming cytogenetics cytomorphology cytopenic details diagnostics dimg dimm discriminating dyspoiesis giving grades granulocytes investigator mfc mfi monocytes multiparameter myelomonocytic outlined panels percentages upcoming weakly	aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified
Tagcloud (Difference) ?		adds capabilities cg challenging comparability confirming cytogenetics cytomorphology cytopenic details diagnostics dimg dimm discriminating dyspoiesis giving grades granulocytes investigator mfc mfi monocytes multiparameter myelomonocytic outlined panels percentages upcoming weakly	aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified
Tagcloud (Intersection) ?