NCAPG2 and TAL1

Number of citations of the paper that reports this interaction (PMID 14729962)
2

Data Source:
HPRD (two hybrid)

		NCAPG2	TAL1
Gene Name		non-SMC condensin II complex, subunit G2	T-cell acute lymphocytic leukemia 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane	Histone Deacetylase Complex Nuclear Chromatin Nucleus Transcription Factor Complex Lsd1/2 Complex
	Molecular Function	Protein Binding Methylated Histone Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Enzyme Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Mitotic Cell Cycle Inner Cell Mass Cell Proliferation Mitotic Nuclear Division Chromosome Condensation Cell Division	Negative Regulation Of Transcription From RNA Polymerase II Promoter Angiogenesis Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Locomotory Behavior Spinal Cord Association Neuron Differentiation Hemopoiesis Erythrocyte Differentiation Megakaryocyte Differentiation Platelet Formation Basophil Differentiation Positive Regulation Of Protein Complex Assembly Embryonic Hemopoiesis Megakaryocyte Development Regulation Of Cell Proliferation Erythrocyte Maturation Cell Fate Commitment Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Chromatin Assembly Or Disassembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Division Astrocyte Fate Commitment Definitive Hemopoiesis Hemangioblast Cell Differentiation Hematopoietic Stem Cell Differentiation Regulation Of Mast Cell Differentiation Regulation Of Stem Cell Maintenance
Pathways		Mitotic Prophase Condensation of Prophase Chromosomes Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: TAL1	23 interactors: CHD3 DRG1 ELSPBP1 EP300 GATA1 GATA2 GATA3 HDAC1 HOXB9 KAT2B KDM1A LMO1 LMO2 MAPK3 NCAPG2 PRKCQ SIN3A SKP2 SP1 STUB1 TCF3 TCF4 ZHX1
Entrez ID		54892	6886
HPRD ID		10539	01753
Ensembl ID		ENSG00000146918	ENSG00000162367
Uniprot IDs		B3KRQ2 F5H7R2 Q86XI2	P17542
PDB IDs			2YPA 2YPB
Enriched GO Terms of Interacting Partners?		Hemangioblast Cell Differentiation Positive Regulation Of Chromatin Assembly Or Disassembly Basophil Differentiation Astrocyte Fate Commitment Regulation Of Mast Cell Differentiation Regulation Of Chromatin Assembly Or Disassembly Primitive Hemopoiesis Hematopoietic Stem Cell Differentiation Erythrocyte Maturation Spinal Cord Association Neuron Differentiation Megakaryocyte Development Granulocyte Differentiation Positive Regulation Of Erythrocyte Differentiation Platelet Formation Platelet Morphogenesis Glial Cell Fate Commitment Megakaryocyte Differentiation Dorsal Spinal Cord Development Definitive Hemopoiesis Regulation Of Stem Cell Maintenance Mesodermal Cell Differentiation Embryonic Hemopoiesis Regulation Of Erythrocyte Differentiation Astrocyte Differentiation Erythrocyte Development Cell Differentiation In Spinal Cord Positive Regulation Of Myeloid Cell Differentiation Mesoderm Formation Mesoderm Morphogenesis Spinal Cord Development Erythrocyte Differentiation Regulation Of Myeloid Leukocyte Differentiation Erythrocyte Homeostasis Myeloid Leukocyte Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Division Formation Of Primary Germ Layer Myeloid Cell Homeostasis Mesoderm Development Cell Maturation Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Protein Complex Assembly Regulation Of Myeloid Cell Differentiation Glial Cell Differentiation Gastrulation Regulation Of Chromosome Organization Central Nervous System Neuron Differentiation Bone Development Locomotory Behavior Homeostasis Of Number Of Cells	Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Embryo Development Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Binding Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Blood Coagulation Hemostasis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromosome Organization Negative Regulation Of Binding Regulation Of Hormone Metabolic Process Regulation Of Erythrocyte Differentiation Regulation Of Body Fluid Levels Biosynthetic Process Wound Healing Hemopoiesis Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Regulation Of Histone Modification Immune System Process
Tagcloud ?		adarb2 asymptomatic carriers carrying ceacam6 cntnap2 col19a1 commonest consider def4 dopaminergic draxin fcer2 functionally g2019s hbg1 idiopathic initiating lrrk2 merit never parkinson pd pvrl2 seq slc2a14 snca tcl1b variations	activates arrest causes complexed contribute e2a expressing fusion heterodimers inhibition interferes jurkat leukemia leukemic line lymphoblastic model oncogene oncogenes originally postulates proposed restored subsequently suggests supporting suppressing transcriptional underwent
Tagcloud (Difference) ?		adarb2 asymptomatic carriers carrying ceacam6 cntnap2 col19a1 commonest consider def4 dopaminergic draxin fcer2 functionally g2019s hbg1 idiopathic initiating lrrk2 merit never parkinson pd pvrl2 seq slc2a14 snca tcl1b variations	activates arrest causes complexed contribute e2a expressing fusion heterodimers inhibition interferes jurkat leukemia leukemic line lymphoblastic model oncogene oncogenes originally postulates proposed restored subsequently suggests supporting suppressing transcriptional underwent
Tagcloud (Intersection) ?