ZRANB1 and DUSP13B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZRANB1	DUSP13B
Description		zinc finger RANBP2-type containing 1	dual specificity phosphatase 13B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm
	Molecular Function	Catalytic Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Hydrolase Activity Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Deubiquitinase Activity	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Hydrolase Activity Phosphatase Activity MAP Kinase Phosphatase Activity
	Biological Process	Autophagosome Assembly Proteolysis Cytoskeleton Organization Wnt Signaling Pathway Cell Migration Protein Deubiquitination Regulation Of Cell Morphogenesis Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Phosphatidylinositol Phosphate Biosynthetic Process Protein K63-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Deubiquitination	Protein Dephosphorylation Spermatogenesis Dephosphorylation Negative Regulation Of MAPK Cascade Meiotic Cell Cycle
Pathways		Degradation of beta-catenin by the destruction complex Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Creatine kinase levels ( 29403010) Height ( 25429064 31562340) Lung cancer ( 34062886)
Interacting Genes		130 interacting genes: AKT1 ARHGEF5 ARRDC2 ARRDC3 ATOSB BAHD1 BRD1 C1orf35 CARD9 CBX7 CBX8 CCDC120 CCDC13 CCDC185 CCDC187 CCHCR1 CCNL1 CDC45 CDK18 CDKL3 CNNM3 CORO7 CPNE7 CWF19L2 DCX DNAJB13 DTNB DUSP13B ENKD1 FAIM FAM124B FAM161A FAM161B FAM50B FAM90A1 FNDC11 GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 HOXB5 HOXC8 IL16 INO80B IP6K3 IQUB JRK KANK2 KIF9 KIFC3 LENG1 LMO3 LNX1 MAGEB4 MAGOH MCRS1 METTL21A MID2 MPPED1 MYEF2 NEK6 NUDT16L1 PHF1 PHF19 PKN1 PLEKHN1 PNMA5 POLDIP3 POLL PPP1R18 PSPC1 RAPGEF3 RASAL3 SCNM1 SDCBP SLC7A11 SNCA STAMBPL1 SUV39H1 SYT17 SYTL4 TBC1D3 TBC1D30 TBC1D3B TBC1D3C TBC1D3G TBC1D3K TCEANC THAP7 TIE1 TLE5 TNS4 TRAF3IP3 TRAF4 TRAF6 TRAPPC2 TRAPPC2B TSGA10IP TSPYL4 TSTD2 TTC23 TWIST1 UBASH3A UBC UBE2D1 UBE2G1 USP2 UVRAG VAV3 WT1 ZBTB24 ZBTB47 ZNF124 ZNF17 ZNF250 ZNF408 ZNF417 ZNF438 ZNF490 ZNF497 ZNF552 ZNF575 ZNF587 ZNF599 ZNF648 ZNF764 ZNF775 ZNF792 ZNF837	14 interacting genes: ACVR1 CALCOCO1 CARD9 CCDC85B HOOK2 HSF2BP INCA1 LMNA PLEKHG4 SH2B2 SMURF1 TGFBR1 TRAF1 ZRANB1
Entrez ID		54764	51207
HPRD ID		11738	13251
Ensembl ID		ENSG00000019995	ENSG00000079393
Uniprot IDs		Q9UGI0	A0A9L9PXN7 Q6B8I1 Q9UII6
PDB IDs		3ZRH 5AF6	2GWO 2PQ5 5XJV
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Zinc Ion Binding Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Nuclear Speck Regulation Of Macromolecule Metabolic Process Microtubule Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process	Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Activin Receptor Complex Activin Receptor Activity, Type I Transforming Growth Factor Beta Receptor Activity, Type I SMAD Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Regulation Of Signal Transduction Negative Regulation Of Apoptotic Signaling Pathway Activin Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Signaling Adaptor Activity Protein Targeting To Vacuole Involved In Autophagy Negative Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway I-SMAD Binding Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Cell Communication Pharyngeal System Development Regulation Of Signaling Negative Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of DNA-binding Transcription Factor Activity Transforming Growth Factor Beta Binding Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Activin Receptor Signaling Pathway Vacuolar Transport Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Ventricular Septum Morphogenesis Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Regulation Of Release Of Cytochrome C From Mitochondria Growth Factor Binding Endocardial Cushion Cell Fate Commitment Signal Transduction Cell Surface Receptor Signaling Pathway Perinuclear Endoplasmic Reticulum Lumen Protein Targeting To Vacuole Regulation Of Neuronal Signal Transduction Engulfment Of Target By Autophagosome Cytosol Positive Regulation Of Epithelial To Mesenchymal Transition Establishment Of Protein Localization To Vacuole Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Determination Of Dorsal Identity Positive Regulation Of Neurofibrillary Tangle Assembly
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