ZRANB1 and POLL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZRANB1	POLL
Description		zinc finger RANBP2-type containing 1	DNA polymerase lambda
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Chromosome Site Of Double-strand Break
	Molecular Function	Catalytic Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Hydrolase Activity Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Deubiquitinase Activity	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity Lyase Activity DNA Polymerase Activity Metal Ion Binding 5'-deoxyribose-5-phosphate Lyase Activity
	Biological Process	Autophagosome Assembly Proteolysis Cytoskeleton Organization Wnt Signaling Pathway Cell Migration Protein Deubiquitination Regulation Of Cell Morphogenesis Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Phosphatidylinositol Phosphate Biosynthetic Process Protein K63-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Deubiquitination	Double-strand Break Repair Via Homologous Recombination DNA Replication DNA Repair Base-excision Repair, Gap-filling Nucleotide-excision Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Damage Response Somatic Hypermutation Of Immunoglobulin Genes DNA Biosynthetic Process
Pathways		Degradation of beta-catenin by the destruction complex Ovarian tumor domain proteases	Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Creatine kinase levels ( 29403010) Height ( 25429064 31562340) Lung cancer ( 34062886)
Interacting Genes		130 interacting genes: AKT1 ARHGEF5 ARRDC2 ARRDC3 ATOSB BAHD1 BRD1 C1orf35 CARD9 CBX7 CBX8 CCDC120 CCDC13 CCDC185 CCDC187 CCHCR1 CCNL1 CDC45 CDK18 CDKL3 CNNM3 CORO7 CPNE7 CWF19L2 DCX DNAJB13 DTNB DUSP13B ENKD1 FAIM FAM124B FAM161A FAM161B FAM50B FAM90A1 FNDC11 GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 HOXB5 HOXC8 IL16 INO80B IP6K3 IQUB JRK KANK2 KIF9 KIFC3 LENG1 LMO3 LNX1 MAGEB4 MAGOH MCRS1 METTL21A MID2 MPPED1 MYEF2 NEK6 NUDT16L1 PHF1 PHF19 PKN1 PLEKHN1 PNMA5 POLDIP3 POLL PPP1R18 PSPC1 RAPGEF3 RASAL3 SCNM1 SDCBP SLC7A11 SNCA STAMBPL1 SUV39H1 SYT17 SYTL4 TBC1D3 TBC1D30 TBC1D3B TBC1D3C TBC1D3G TBC1D3K TCEANC THAP7 TIE1 TLE5 TNS4 TRAF3IP3 TRAF4 TRAF6 TRAPPC2 TRAPPC2B TSGA10IP TSPYL4 TSTD2 TTC23 TWIST1 UBASH3A UBC UBE2D1 UBE2G1 USP2 UVRAG VAV3 WT1 ZBTB24 ZBTB47 ZNF124 ZNF17 ZNF250 ZNF408 ZNF417 ZNF438 ZNF490 ZNF497 ZNF552 ZNF575 ZNF587 ZNF599 ZNF648 ZNF764 ZNF775 ZNF792 ZNF837	42 interacting genes: APP ATM CCNDBP1 CDK1 CDK2 CMTM5 FAM9B FSD2 GOLGA6L9 HMBOX1 HUWE1 KRT16 KRT19 KRT27 KRT40 KRTAP10-3 KRTAP10-7 LCN2 LDOC1 MAGEA12 MAGEA2 MAGEA2B MAL2 MCC MDFI PCNA PICK1 PNMA1 PRKD3 REV1 RPA1 SSX2IP TFCP2 TFIP11 TNFRSF10D TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H ZRANB1
Entrez ID		54764	27343
HPRD ID		11738	09394
Ensembl ID		ENSG00000019995	ENSG00000166169
Uniprot IDs		Q9UGI0	A8K860 B4DE17 Q5JQP8 Q9UGP5
PDB IDs		3ZRH 5AF6	1NZP 1RZT 1XSL 1XSN 1XSP 2BCQ 2BCR 2BCS 2BCU 2BCV 2GWS 2JW5 2PFN 2PFO 2PFP 2PFQ 3C5F 3C5G 3HW8 3HWT 3HX0 3MDA 3MDC 3MGH 3MGI 3PML 3PMN 3PNC 3UPQ 3UQ0 3UQ2 4FO6 4K4G 4K4H 4K4I 4X5V 4XA5 4XQ8 4XRH 4XUS 5CA7 5CB1 5CHG 5CJ7 5CP2 5CR0 5CWR 5DDM 5DDY 5DKW 5III 5IIJ 5IIK 5IIL 5IIM 5IIN 5IIO 5W4G 7M07 7M08 7M09 7M0A 7M0B 7M0C 7M0D 7M0E 7M43 7M44 7M45 7M46 7M47 7M48 7M49 7M4A 7M4B 7M4C 7M4D 7M4E 7M4F 7M4G 7M4H 7M4I 7M4J 7M4K 7M4L 7UN7 8U0O
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Zinc Ion Binding Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Nuclear Speck Regulation Of Macromolecule Metabolic Process Microtubule Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process	Ubiquitin Conjugating Enzyme Activity Telomere Maintenance Chromosome, Telomeric Region Keratin Filament Protein K48-linked Ubiquitination Telomere Organization Ubiquitin-protein Transferase Activity DNA Biosynthetic Process Intermediate Filament Post-translational Protein Modification Protein Polyubiquitination Nucleus DNA Metabolic Process Protein Monoubiquitination Structural Constituent Of Skin Epidermis Cellular Senescence Cyclin-dependent Protein Kinase Activity Chromosome Organization DNA Repair DNA Replication Intermediate Filament Organization Protein Localization To Site Of Double-strand Break Negative Regulation Of Protein Acetylation Negative Regulation Of Transcription By RNA Polymerase II Protein Modification Process Histone Kinase Activity Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process DNA Damage Response Protein Ubiquitination Protection From Non-homologous End Joining At Telomere Cellular Response To Reactive Oxygen Species Positive Regulation Of DNA Replication Positive Regulation Of Protein Ubiquitination PML Body Cyclin-dependent Protein Kinase Holoenzyme Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification By Small Protein Conjugation Cellular Response To X-ray Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus Positive Regulation Of Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Epithelial Cell Differentiation Modification-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Protein Binding DNA Strand Resection Involved In Replication Fork Processing Telomere Maintenance In Response To DNA Damage
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