DUSP13B

Description		dual specificity phosphatase 13B
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GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Hydrolase Activity Phosphatase Activity MAP Kinase Phosphatase Activity
	Biological Process	Protein Dephosphorylation Spermatogenesis Dephosphorylation Negative Regulation Of MAPK Cascade Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: CLU
Interacting Genes		14 interacting genes: ACVR1 CALCOCO1 CARD9 CCDC85B HOOK2 HSF2BP INCA1 LMNA PLEKHG4 SH2B2 SMURF1 TGFBR1 TRAF1 ZRANB1
Entrez ID		51207
HPRD ID		13251
Ensembl ID		ENSG00000079393
Uniprot IDs		A0A9L9PXN7 Q6B8I1 Q9UII6
PDB IDs		2GWO 2PQ5 5XJV
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Activin Receptor Complex Activin Receptor Activity, Type I Transforming Growth Factor Beta Receptor Activity, Type I SMAD Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Regulation Of Signal Transduction Negative Regulation Of Apoptotic Signaling Pathway Activin Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Signaling Adaptor Activity Protein Targeting To Vacuole Involved In Autophagy Negative Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway I-SMAD Binding Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Cell Communication Pharyngeal System Development Regulation Of Signaling Negative Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of DNA-binding Transcription Factor Activity Transforming Growth Factor Beta Binding Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Activin Receptor Signaling Pathway Vacuolar Transport Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of DNA-binding Transcription Factor Activity Ventricular Septum Morphogenesis Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Regulation Of Release Of Cytochrome C From Mitochondria Growth Factor Binding Endocardial Cushion Cell Fate Commitment Signal Transduction Cell Surface Receptor Signaling Pathway Perinuclear Endoplasmic Reticulum Lumen Protein Targeting To Vacuole Regulation Of Neuronal Signal Transduction Engulfment Of Target By Autophagosome Cytosol Positive Regulation Of Epithelial To Mesenchymal Transition Establishment Of Protein Localization To Vacuole Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Determination Of Dorsal Identity Positive Regulation Of Neurofibrillary Tangle Assembly
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