AKAP14 and ROPN1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AKAP14	ROPN1L
Description		A-kinase anchoring protein 14	rhophilin associated tail protein 1 like
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axoneme CAMP-dependent Protein Kinase Complex	Radial Spoke Extracellular Region Nucleoplasm Cytoplasm Cilium Motile Cilium Cell Projection
	Molecular Function	Protein Binding Protein Kinase A Regulatory Subunit Binding	Protein Binding Identical Protein Binding
	Biological Process		Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Flagellated Sperm Motility Sperm Capacitation
Pathways
Drugs
Diseases
GWAS			Body mass index ( 22446040) Breast cancer ( 21424380) Coronary artery disease in type 1 diabetes ( 29695241) Dermatomyositis or juvenile dermatomyositis ( 26362759) Mean arterial pressure ( 27618448) Triglyceride levels ( 31170924)
Interacting Genes		8 interacting genes: DPY30 FBXO7 PRKACA PRKAR1B PRKAR2A PRKAR2B ROPN1 ROPN1L	7 interacting genes: AKAP14 AKAP3 AKAP5 AKAP7 APP BEX2 RSPH3
Entrez ID		158798	83853
HPRD ID		02353	17986
Ensembl ID		ENSG00000186471	ENSG00000145491
Uniprot IDs		Q86UN6	Q96C74
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		CAMP-dependent Protein Kinase Complex Ciliary Base CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Protein Kinase A Catalytic Subunit Binding Sperm Capacitation CAMP Binding Negative Regulation Of CAMP/PKA Signal Transduction Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Ubiquitin Protein Ligase Binding Negative Regulation Of Intracellular Signal Transduction Nucleotide-activated Protein Kinase Complex Cell Maturation Developmental Maturation Motile Cilium Plasma Membrane Raft Protein Domain Specific Binding Postsynapse Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Negative Regulation Of Cell Communication G Protein-coupled Receptor Signaling Pathway Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of Intracellular Signal Transduction Protein Kinase Binding Response To Antipsychotic Drug Modulation Of Chemical Synaptic Transmission Axoneme Lewy Body Core Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Cilium Glutamatergic Synapse Centrosome CAMP-dependent Protein Kinase Activity Cilium Movement Channel Activator Activity Regulation Of Macroautophagy Positive Regulation Of Fear Response CAMP/PKA Signal Transduction Vascular Endothelial Cell Response To Laminar Fluid Shear Stress	Protein Kinase A Binding Protein Kinase A Regulatory Subunit Binding Positive Regulation Of Long-term Synaptic Potentiation Dendrite Membrane Regulation Of Long-term Synaptic Potentiation Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Calcium-mediated Signaling Cellular Response To CAMP Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Monoatomic Ion Transport Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Metal Ion Transport Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Response To CAMP Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Modulation Of Chemical Synaptic Transmission Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cell Projection Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Endosome To Plasma Membrane Protein Transport Response To Purine-containing Compound Regulation Of Calcium Ion Transmembrane Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Positive Regulation Of Synaptic Transmission Astrocyte Activation Involved In Immune Response Dendritic Spine Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Calcium-mediated Signaling Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding
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