SCAND2P and CHRM5

		SCAND2P	CHRM5
Description		SCAN domain containing 2 pseudogene	cholinergic receptor muscarinic 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane Membrane Dendrite Synapse Postsynaptic Membrane
	Molecular Function	DNA-binding Transcription Factor Activity	Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Gastric Acid Secretion Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation Acetylcholine Receptor Signaling Pathway
Pathways			Muscarinic acetylcholine receptors G alpha (q) signalling events
Drugs			Ziprasidone Amitriptyline Metixene Terfenadine Clozapine Doxylamine Trihexyphenidyl Loxapine Meperidine Imipramine Gallamine triethiodide Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Brompheniramine Maprotiline Methantheline Glycopyrronium Bethanechol Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Methacholine Aclidinium Umeclidinium Dosulepin Etoperidone Homatropine Thonzylamine Revefenacin Propiverine Rociverine Aripiprazole lauroxil
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Schizophrenia ( 29483656)	Malaria ( 31844061)
Interacting Genes		1 interacting genes: APP	31 interacting genes: ASPH ASTN2 ATP2A2 ATP9A CBFB CD82 EPB41L1 EPC1 ERCC1 GJB6 GOLGA8A GPRASP1 HLA-F MAP3K1 MSMO1 MYH7 NLE1 NPAS3 PRSS16 REEP5 RGS7 RTN1 SLC2A6 SLC5A6 SLC6A8 SMAD6 SNCA SPNS1 STARD3NL TMEM161A USP33
Entrez ID		54581	1133
HPRD ID		18021	00331
Ensembl ID			ENSG00000184984
Uniprot IDs			P08912 Q8IVW0
PDB IDs			6OL9
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Low-density Lipoprotein Particle Mediated Signaling G Protein-coupled Acetylcholine Receptor Activity Regulation Of Phosphatidylinositol Dephosphorylation Single-stranded DNA 3'-5' DNA Exonuclease Activity Exoribonuclease II Activity ERK5 Cascade Ventricular Cardiac Myofibril Assembly Cytidine Transmembrane Transporter Activity Pyrimidine- And Adenosine-specific:sodium Symporter Activity Nucleoside:sodium Symporter Activity Uridine Transmembrane Transport Azole Transmembrane Transporter Activity Cytidine Transport Purine Nucleobase Transmembrane Transporter Activity Pyrimidine Nucleoside Transport Nucleoside Transmembrane Transporter Activity Nucleoside Import Across Plasma Membrane Uridine Transmembrane Transporter Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway	Sarcoplasmic Reticulum Membrane Transition Between Fast And Slow Fiber Negative Regulation Of Exocytosis Sarcoplasmic Reticulum Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Skeletal Muscle Adaptation Supramolecular Fiber Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Transmembrane Transporter Activity Regulation Of Exocytosis Endoplasmic Reticulum Membrane Organization
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