CHRM5 and GOLGA8A

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		CHRM5	GOLGA8A
Description		cholinergic receptor muscarinic 5	golgin A8 family member A
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Synapse Postsynaptic Membrane	Golgi Cis Cisterna Golgi Apparatus Cis-Golgi Network Cytosol Membrane Golgi Cisterna Membrane
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity
	Biological Process	Gastric Acid Secretion Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation Acetylcholine Receptor Signaling Pathway	Golgi Organization
Pathways		Muscarinic acetylcholine receptors G alpha (q) signalling events
Drugs		Ziprasidone Amitriptyline Metixene Terfenadine Clozapine Doxylamine Trihexyphenidyl Loxapine Meperidine Imipramine Gallamine triethiodide Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Brompheniramine Maprotiline Methantheline Glycopyrronium Bethanechol Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Methacholine Aclidinium Umeclidinium Dosulepin Etoperidone Homatropine Thonzylamine Revefenacin Propiverine Rociverine Aripiprazole lauroxil
Diseases
GWAS		Malaria ( 31844061)
Interacting Genes		31 interacting genes: ASPH ASTN2 ATP2A2 ATP9A CBFB CD82 EPB41L1 EPC1 ERCC1 GJB6 GOLGA8A GPRASP1 HLA-F MAP3K1 MSMO1 MYH7 NLE1 NPAS3 PRSS16 REEP5 RGS7 RTN1 SLC2A6 SLC5A6 SLC6A8 SMAD6 SNCA SPNS1 STARD3NL TMEM161A USP33	3 interacting genes: CHRM5 HSPB1 ITSN2
Entrez ID		1133	23015
HPRD ID		00331	09974
Ensembl ID		ENSG00000184984	ENSG00000175265
Uniprot IDs		P08912 Q8IVW0	A0A8V8TPN8 A0AAG2UVG6 A0AAG2UVS0 A7E2F4
PDB IDs		6OL9
Enriched GO Terms of Interacting Partners?		Sarcoplasmic Reticulum Membrane Transition Between Fast And Slow Fiber Negative Regulation Of Exocytosis Sarcoplasmic Reticulum Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Skeletal Muscle Adaptation Supramolecular Fiber Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Transmembrane Transporter Activity Regulation Of Exocytosis Endoplasmic Reticulum Membrane Organization	G Protein-coupled Acetylcholine Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Gastric Acid Secretion Regulation Of Phosphatidylinositol Dephosphorylation Regulation Of Protein Kinase C Signaling Negative Regulation Of Protein Kinase C Signaling Anterograde Axonal Protein Transport Protein Kinase C Inhibitor Activity Clathrin-dependent Synaptic Vesicle Endocytosis Regulation Of Phosphorus Metabolic Process Regulation Of Dephosphorylation Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity G Protein-coupled Acetylcholine Receptor Signaling Pathway Transmission Of Nerve Impulse Dopamine Transport Positive Regulation Of Endothelial Cell Chemotaxis Protein Transport Along Microtubule Contractile Muscle Fiber Positive Regulation Of Dendrite Extension Intracellular Vesicle Acid Secretion Protein Refolding Monoamine Transport Cellular Response To Vascular Endothelial Growth Factor Stimulus Clathrin-dependent Endocytosis Regulation Of Phospholipid Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Acetylcholine Receptor Signaling Pathway Regulation Of Anatomical Structure Morphogenesis Anterograde Axonal Transport Synaptic Vesicle Endocytosis Presynaptic Endocytosis Postsynaptic Signal Transduction Protein Kinase C Binding Platelet Aggregation Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Protein Localization To Synapse Positive Regulation Of Blood Vessel Endothelial Cell Migration Protein Folding Chaperone Axon Cytoplasm Positive Regulation Of Interleukin-1 Beta Production Axonal Transport Cornified Envelope Proteasome Complex Homotypic Cell-cell Adhesion
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