SPSB4

Gene Name		splA/ryanodine receptor domain and SOCS box containing 4
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Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Stroke (ischemic) ( 23041239)
Protein-protein Interactions		3 interactors: DDX4 NOS2 PAWR
Entrez ID		92369
HPRD ID		18108
Ensembl ID		ENSG00000175093
Uniprot IDs		Q96A44
PDB IDs		2V24
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Peptidyl-cysteine S-nitrosylation Interleukin-2 Biosynthetic Process Germ-line Stem Cell Maintenance Regulation Of Amyloid Precursor Protein Biosynthetic Process Interleukin-2 Production Arginine Catabolic Process Positive Regulation Of Killing Of Cells Of Other Organism Regulation Of Killing Of Cells Of Other Organism Positive Regulation Of Guanylate Cyclase Activity Spermatogenesis Male Gamete Generation Regulation Of Cellular Respiration Positive Regulation Of Glycoprotein Biosynthetic Process Nitric Oxide Biosynthetic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Glycoprotein Metabolic Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of B Cell Proliferation Innate Immune Response In Mucosa Positive Regulation Of CGMP Biosynthetic Process Gamete Generation Positive Regulation Of CGMP Metabolic Process Organelle Organization Arginine Metabolic Process Negative Regulation Of T Cell Receptor Signaling Pathway RNA Metabolic Process Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Meiotic Nuclear Division Regulation Of CGMP Biosynthetic Process Cytokine Biosynthetic Process Regulation Of Protein Localization Sexual Reproduction Regulation Of Glycoprotein Biosynthetic Process Multicellular Organismal Reproductive Process Negative Regulation Of Meiotic Cell Cycle Nitric Oxide Metabolic Process Male Meiosis I Multicellular Organism Reproduction Cytokine Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of CGMP Metabolic Process Positive Regulation Of Vasodilation Mucosal Immune Response PiRNA Metabolic Process Defense Response To Gram-negative Bacterium Negative Regulation Of B Cell Activation Superoxide Metabolic Process Regulation Of Meiosis Reproduction
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