SASS6 and FBXW5

Number of citations of the paper that reports this interaction (PMID 21725316)
24

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study)

		SASS6	FBXW5
Gene Name		spindle assembly 6 homolog (C. elegans)	F-box and WD repeat domain containing 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Centriole Deuterosome	Cytoplasm SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding
	Biological Process	Centriole Replication Centrosome Duplication	Mitotic Nuclear Division Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Centrosome Duplication
Pathways			Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: FBXW5	16 interactors: ADAMTSL4 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP9-4 MDFI MYB NLK NOTCH2NL SASS6 SKP1 TRIM27 TSC2 UBE2R2
Entrez ID		163786	54461
HPRD ID		10907	10955
Ensembl ID		ENSG00000156876	ENSG00000159069
Uniprot IDs		F5GXY5 Q6UVJ0	Q969U6
PDB IDs
Enriched GO Terms of Interacting Partners?		SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Centrosome Duplication Centrosome Cycle Centrosome Organization Microtubule Organizing Center Organization	Negative Regulation Of Wnt Signaling Pathway Protein Monoubiquitination Regulation Of Wnt Signaling Pathway
Tagcloud ?			autophagic autophagy brains competes cul4 da dopaminergic dysfunctional dysregulated exclusive hydroxydopamine implicating l1 mortem mtor neurochem neurodegeneration ohda opposition os oxi parkinson pathogenic proteasomal stabilize stabilizes tnfaip8 tsc2 tuberous
Tagcloud (Difference) ?			autophagic autophagy brains competes cul4 da dopaminergic dysfunctional dysregulated exclusive hydroxydopamine implicating l1 mortem mtor neurochem neurodegeneration ohda opposition os oxi parkinson pathogenic proteasomal stabilize stabilizes tnfaip8 tsc2 tuberous
Tagcloud (Intersection) ?