TAF7L and TAF1

Number of citations of the paper that reports this interaction (PMID 12665565)
29

Data Source:
BioGRID (two hybrid)

		TAF7L	TAF1
Gene Name		TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIID Complex Cytoplasm	Nucleoplasm Transcription Factor TFIID Complex MLL1 Complex
	Molecular Function	Molecular_function	P53 Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding TBP-class Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Multicellular Organismal Development Spermatogenesis Biological_process Cell Differentiation	DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Cell Cycle Gene Expression Viral Process Histone Acetylation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autophosphorylation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways			RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP SRPK2 TAF1 TBP	47 interactors: APC AR ASF1A ASF1B BRMS1 CCNA2 CCND1 EDF1 EWSR1 FOS GFI1B GTF2A1 GTF2E1 GTF2F1 HIST1H3A HIST1H4A HIST3H3 HMGB1 HSF1 JUN MAX MDM2 MSX1 PAX3 RANBP2 RB1 RBL1 RBL2 RELA SUB1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF8 TAF9 TBP TP53 UBE2I UBTF
Entrez ID		54457	6872
HPRD ID		02259	02436
Ensembl ID		ENSG00000102387	ENSG00000147133
Uniprot IDs		Q5H9L4	P21675
PDB IDs			1EQF 3AAD 3UV4 3UV5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Nuclear Speck Organization Transcription Initiation From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Collateral Sprouting In Absence Of Injury RNA Polymerase II Transcriptional Preinitiation Complex Assembly DNA-templated Transcription, Initiation Protein Phosphorylation Positive Regulation Of Transcription, DNA-templated Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Macromolecule Biosynthetic Process Axon Choice Point Recognition Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Phosphorylation MRNA Processing Regulation Of Gene Expression Cellular Component Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Chromatin Silencing At RDNA Positive Regulation Of DNA-templated Transcription, Initiation MRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Viral Process RNA Processing Positive Regulation Of Viral Genome Replication Regulation Of DNA-templated Transcription, Initiation Copper Ion Homeostasis Suckling Behavior Cellular Macromolecular Complex Assembly Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of Proteolysis	RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Viral Process Regulation Of Metabolic Process Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Chromatin Organization Positive Regulation Of Cellular Metabolic Process Chromosome Organization Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Chromatin Modification Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organelle Organization Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Replication-dependent Nucleosome Assembly Mitotic Cell Cycle
Tagcloud ?		azoospermia basepair bc043391 caucasian ethnic evolved exception exon flanking follicle fsh gonadal hormones infertile infertility intron introns mammals ncbi nonobstructive recruited reproductive semen specialised speculated spermatogenesis spermatogenic testicular trf	3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf7 tata tfiid trimethylated
Tagcloud (Difference) ?		azoospermia basepair bc043391 caucasian ethnic evolved exception exon flanking follicle fsh gonadal hormones infertile infertility intron introns mammals ncbi nonobstructive recruited reproductive semen specialised speculated spermatogenesis spermatogenic testicular trf	3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf7 tata tfiid trimethylated
Tagcloud (Intersection) ?