ANLN and SEPTIN7

Number of citations of the paper that reports this interaction (PubMedID 10931866)
55

Data Source:
HPRD (in vitro)

		ANLN	SEPTIN7
Description		anillin, actin binding protein	septin 7
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Actomyosin Contractile Ring Cytosol Cytoskeleton Cell Cortex Actin Cytoskeleton Midbody Bleb Cell Projection	Chromosome, Centromeric Region Kinetochore Stress Fiber Nucleus Chromosome Cytoplasm Spindle Cytosol Cytoskeleton Cilium Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Motile Cilium Cell Division Site Cleavage Furrow Cell Projection Extracellular Exosome Sperm Annulus Non-motile Cilium
	Molecular Function	Actin Binding Protein Binding Cadherin Binding	Nucleotide Binding GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Mitotic Cytokinesis Actomyosin Contractile Ring Assembly Septin Ring Assembly Hematopoietic Progenitor Cell Differentiation Regulation Of Exit From Mitosis Septin Ring Organization Cell Division Podocyte Cell Migration Positive Regulation Of Bleb Assembly	Spermatogenesis Intracellular Protein Localization Regulation Of Embryonic Cell Shape Cell Differentiation Cell Division Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Red cell distribution width ( 32888494) Systolic blood pressure ( 26969751)
Interacting Genes		8 interacting genes: CEBPA CRK FOXP1 FZR1 MARCHF10 SEPTIN7 SUMO2 USP10	15 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE GRIK1 HDAC6 LINC01554 OGT PCNT REL S100A4 SEPTIN11 SEPTIN5 SEPTIN9
Entrez ID		54443	989
HPRD ID		09799	04398
Ensembl ID		ENSG00000011426	ENSG00000122545
Uniprot IDs		A8K5D9 Q9NQW6	A0A023T695 A0A024RA87 A8K3D0 B4DNE4 G3V1Q4 Q16181
PDB IDs		2Y7B 4XH3 4XOI	2QAG 3T5D 3TW4 6N0B 6N12 6UQQ 7M6J 8SJJ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Response To Peptide Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Protein Modification By Small Protein Conjugation Post-translational Protein Modification RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Embryonic Cell Shape Regulation Of Protein Catabolic Process Cellular Response To Tumor Necrosis Factor Cellular Response To Cytokine Stimulus Regulation Of Proteolysis Response To Vitamin B2 C/EBP Complex Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Negative Regulation Of Stress Granule Assembly DNA Biosynthetic Process Positive Regulation Of Interleukin-21 Production Kinase Binding Regulation Of Organelle Organization CHOP-C/EBP Complex Response To Tumor Necrosis Factor Cerebellar Neuron Development DNA Synthesis Involved In Mitotic DNA Replication Response To Cytokine Regulation Of Cell Shape Positive Regulation Of Catabolic Process White Fat Cell Proliferation Myeloid Leukocyte Differentiation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Signal Transduction In Response To DNA Damage Protein Ubiquitination Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Thymidine Biosynthetic Process Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Cellular Component Organization Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Response To Phenylpropanoid Diapedesis	Microtubule Cytoskeleton Cytoskeleton Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Septin Ring Septin Complex Positive Regulation Of Pseudopodium Assembly Cell Division Site Positive Regulation Of Cell Projection Organization Cytoskeleton-dependent Cytokinesis Regulation Of Cell Projection Assembly Positive Regulation Of Cellular Component Biogenesis Septin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Molecular Adaptor Activity Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein-containing Complex Assembly Rho Protein Signal Transduction Cell Division Regulation Of Cell Morphogenesis Positive Regulation Of Protein Polymerization Membraneless Organelle Assembly Regulation Of Actin Filament Polymerization Microtubule Regulation Of Cell Shape Positive Regulation Of Cellular Component Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Organelle Assembly Regulation Of Supramolecular Fiber Organization Regulation Of Organelle Organization Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Regulation Of Cellular Component Organization Positive Regulation Of Cytoskeleton Organization Intracellular Signaling Cassette Microtubule Plus-end Directed Mitotic Chromosome Migration Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation Positive Regulation Of Organelle Organization Cytoskeletal Regulatory Protein Binding Septin Ring Assembly Regulation Of Cytoskeleton Organization Mitophagy Cytoskeleton Organization Regulation Of Cellular Component Size
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