GFOD1 and HSF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GFOD1	HSF4
Description		Gfo/Idh/MocA-like oxidoreductase domain containing 1	heat shock transcription factor 4
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GO Annotations	Cellular Component	Extracellular Region	Chromatin Nucleus Nuclear Speck
	Molecular Function	Nucleotide Binding Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Phosphatase Binding Identical Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Lens Fiber Cell Differentiation
Pathways		RHOQ GTPase cycle
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Coronary artery disease ( 33020668)
Interacting Genes		8 interacting genes: FAM9B HSF4 KRT31 KRT40 KRTAP10-3 KRTAP10-8 MAGEA6 NOTCH2NLA	43 interacting genes: ACTMAP AKAP8L ALKBH4 C10orf55 CDK2AP2 DAXX DUSP26 FAM168B FAM200C FOXH1 FOXI1 GFOD1 HGS INTS11 KRT31 KRT37 KRT38 KRT40 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP6-2 MAPK1 MAPK14 MAPK3 MAPK8 MKRN3 NHLRC4 NUDT21 NUP62 OIP5 PIH1D2 PITX1 PLA2G10 PPFIBP2 SESTD1 SLC27A5 SMARCA4 SOX10 TPM3 UFSP1 YTHDF1 ZMYND12
Entrez ID		54438	3299
HPRD ID		13574	03896
Ensembl ID		ENSG00000145990	ENSG00000102878
Uniprot IDs		Q9NXC2 S4R302	Q9ULV5
PDB IDs		8Y7P	6J6V 6J6W
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Epithelial Cell Differentiation Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Meiotic Cell Cycle Structural Molecule Activity	Intermediate Filament MAP Kinase Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Keratin Filament Protein Binding Structural Constituent Of Skin Epidermis Interleukin-34-mediated Signaling Pathway Positive Regulation Of Cyclase Activity Nuclear Androgen Receptor Binding Intermediate Filament Organization Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Anatomical Structure Morphogenesis Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Lipopolysaccharide-mediated Signaling Pathway Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Morphogenesis Of An Epithelium Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Bergmann Glial Cell Differentiation MAPK Cascade Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Cellular Senescence Tissue Morphogenesis Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Glial Cell Development Negative Regulation Of Cholesterol Efflux Regulation Of Gene Expression P53 Binding Regulation Of Golgi Organization Pseudopodium Negative Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Macrophage Chemotaxis Animal Organ Formation Negative Regulation Of Cholesterol Transport
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