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SSH1 and DSTN
Number of citations of the paper that reports this interaction (PMID
11832213
)
123
Data Source:
BioGRID
(enzymatic study)
SSH1
DSTN
Gene Name
slingshot protein phosphatase 1
destrin (actin depolymerizing factor)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytoskeleton
Plasma Membrane
Lamellipodium
Midbody
Cleavage Furrow
Actin Cytoskeleton
Cortical Actin Cytoskeleton
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
Actin Binding
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Binding
Protein Tyrosine/serine/threonine Phosphatase Activity
Actin Binding
Biological Process
Cell Morphogenesis
Protein Dephosphorylation
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Lamellipodium Assembly
Actin Cytoskeleton Organization
Regulation Of Cellular Protein Metabolic Process
Peptidyl-tyrosine Dephosphorylation
Regulation Of Axonogenesis
Cellular Response To ATP
Movement Of Cell Or Subcellular Component
Actin Polymerization Or Depolymerization
Actin Filament Depolymerization
Positive Regulation Of Actin Filament Depolymerization
Actin Filament Severing
Pathways
Drugs
Diseases
GWAS
Presence of antiphospholipid antibodies (
23509613
)
Protein-Protein Interactions
5 interactors:
ACTB
CFL1
CFL2
CORO1B
DSTN
8 interactors:
ACTB
ACTG1
CFL2
SHBG
SMAD9
SSH1
TAX1BP1
TESK2
Entrez ID
54434
11034
HPRD ID
09486
16446
Ensembl ID
ENSG00000084112
ENSG00000125868
Uniprot IDs
Q8WYL5
P60981
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Actin Filament Depolymerization
Actin Filament Depolymerization
Positive Regulation Of Protein Depolymerization
Positive Regulation Of Protein Complex Disassembly
Actin Filament Organization
Regulation Of Actin Filament Depolymerization
Regulation Of Actin Cytoskeleton Organization
Actin Polymerization Or Depolymerization
Regulation Of Actin Filament-based Process
Regulation Of Protein Depolymerization
Regulation Of Cytoskeleton Organization
Regulation Of Protein Complex Disassembly
Actin Cytoskeleton Organization
Actin Filament-based Process
Cellular Protein Complex Disassembly
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Polymerization Or Depolymerization
Protein Complex Disassembly
Regulation Of Actin Filament Length
Regulation Of Organelle Organization
Regulation Of Dendritic Spine Morphogenesis
Cytoskeleton Organization
Regulation Of Cellular Component Size
Regulation Of Dendritic Spine Development
Organelle Organization
Positive Regulation Of Organelle Organization
Movement Of Cell Or Subcellular Component
Regulation Of Cell Morphogenesis
Regulation Of Cell Projection Organization
Regulation Of Dendrite Morphogenesis
Wound Healing
Chemotaxis
Ephrin Receptor Signaling Pathway
Regulation Of Dendrite Development
Regulation Of Cellular Component Organization
Response To Wounding
Protein Localization To Cell Leading Edge
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Ameboidal-type Cell Migration
Positive Regulation Of Lamellipodium Morphogenesis
Platelet Activation
Actin Filament Branching
Cell Projection Organization
Phagocytosis
Fc Receptor Signaling Pathway
Regulation Of Lamellipodium Morphogenesis
Locomotion
Immune Response-activating Cell Surface Receptor Signaling Pathway
Adherens Junction Organization
Actin Cytoskeleton Organization
Cell Junction Assembly
Actin Filament-based Process
Cell-cell Junction Organization
Platelet Aggregation
Sarcomere Organization
Retina Homeostasis
Myofibril Assembly
Cytoskeleton Organization
Primary Spermatocyte Growth
Midbrain Development
Nervous System Development
Ephrin Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Actomyosin Structure Organization
Generation Of Neurons
Striated Muscle Cell Development
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Neurogenesis
Muscle Cell Development
Anatomical Structure Development
Tissue Homeostasis
Organelle Organization
Platelet Activation
Cell Development
Innate Immune Response
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Cellular Component Assembly
Cell Differentiation
Striated Muscle Cell Differentiation
Mullerian Duct Regression
Enzyme Linked Receptor Protein Signaling Pathway
Multicellular Organismal Homeostasis
Developmental Process
Cellular Response To ATP
Phagocytosis
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Cell Morphogenesis
Positive Regulation Of Actin Filament Depolymerization
Muscle Cell Differentiation
Regulation Of Cellular Component Size
Homotypic Cell-cell Adhesion
System Development
Single Organism Reproductive Process
Tagcloud
?
10mum
20days
aging
cofilin1
compartments
cytoskeleton
decline
dysregulation
inactivation
interestingly
knock
lim
limk1
mef
mefdko
occurring
pcns
plasticity
presenilin
ps1
regard
remodeling
rescued
safely
secretase
shed
shh1
slingshot
stream
Tagcloud (Difference)
?
10mum
20days
aging
cofilin1
compartments
cytoskeleton
decline
dysregulation
inactivation
interestingly
knock
lim
limk1
mef
mefdko
occurring
pcns
plasticity
presenilin
ps1
regard
remodeling
rescued
safely
secretase
shed
shh1
slingshot
stream
Tagcloud (Intersection)
?