SSH1 and CORO1B

Number of citations of the paper that reports this interaction (PMID 17350576)
61

Data Source:
HPRD (in vitro, in vivo)

		SSH1	CORO1B
Gene Name		slingshot protein phosphatase 1	coronin, actin binding protein, 1B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Lamellipodium Midbody Cleavage Furrow	Stress Fiber Cytoplasm Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Lamellipodium Cell Leading Edge Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Actin Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity	Protein Binding Identical Protein Binding Actin Filament Binding Arp2/3 Complex Binding
	Biological Process	Cell Morphogenesis Protein Dephosphorylation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Lamellipodium Assembly Actin Cytoskeleton Organization Regulation Of Cellular Protein Metabolic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Axonogenesis Cellular Response To ATP	Cell Migration Actin Cytoskeleton Organization Ruffle Organization Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endothelial Cell Chemotaxis Wound Healing Actin Filament Bundle Assembly Actin Filament Branching Protein Localization To Cell Leading Edge Positive Regulation Of Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ACTB CFL1 CFL2 CORO1B DSTN	6 interactors: ARPC2 KPNA2 POLR1C PRKCA SSH1 TERF1
Entrez ID		54434	57175
HPRD ID		09486	16743
Ensembl ID		ENSG00000084112	ENSG00000172725
Uniprot IDs		Q8WYL5	Q9BR76
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Actin Filament Depolymerization Actin Filament Depolymerization Positive Regulation Of Protein Depolymerization Positive Regulation Of Protein Complex Disassembly Actin Filament Organization Regulation Of Actin Filament Depolymerization Regulation Of Actin Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Actin Filament-based Process Regulation Of Protein Depolymerization Regulation Of Cytoskeleton Organization Regulation Of Protein Complex Disassembly Actin Cytoskeleton Organization Actin Filament-based Process Cellular Protein Complex Disassembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Protein Complex Disassembly Regulation Of Actin Filament Length Regulation Of Organelle Organization Regulation Of Dendritic Spine Morphogenesis Cytoskeleton Organization Regulation Of Cellular Component Size Regulation Of Dendritic Spine Development Organelle Organization Positive Regulation Of Organelle Organization Movement Of Cell Or Subcellular Component Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Dendrite Morphogenesis Wound Healing Chemotaxis Ephrin Receptor Signaling Pathway Regulation Of Dendrite Development Regulation Of Cellular Component Organization Response To Wounding Protein Localization To Cell Leading Edge Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Ameboidal-type Cell Migration Positive Regulation Of Lamellipodium Morphogenesis Platelet Activation Actin Filament Branching Cell Projection Organization Phagocytosis Fc Receptor Signaling Pathway Regulation Of Lamellipodium Morphogenesis Locomotion Immune Response-activating Cell Surface Receptor Signaling Pathway	Regulation Of Lamellipodium Assembly Positive Regulation Of Cellular Component Biogenesis Regulation Of Cytoskeleton Organization Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Protein Polymerization Positive Regulation Of Mitotic Cell Cycle Regulation Of Cell Projection Assembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Histone H3-T6 Phosphorylation Innate Immune Response Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Protein Complex Assembly Telomere Maintenance Via Telomere Shortening Regulation Of Organelle Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Telomere Maintenance Via Telomerase Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Response To Stimulus Positive Regulation Of Cell Cycle Desmosome Assembly Replicative Cell Aging Cellular Response To ATP Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Transferase Activity Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Cellular Component Size Negative Regulation Of Glucose Import Regulation Of Telomere Maintenance Via Telomerase Regulation Of Protein Complex Assembly Immune Response Positive Regulation Of Macrophage Differentiation Defense Response Desmosome Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cell Adhesion Organelle Organization Regulation Of Telomerase Activity Positive Regulation Of Lamellipodium Assembly Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process
Tagcloud ?		10mum 20days aging cofilin1 compartments cytoskeleton decline dysregulation inactivation interestingly knock lim limk1 mef mefdko occurring pcns plasticity presenilin ps1 regard remodeling rescued safely secretase shed shh1 slingshot stream	abomasum actb b2m blat butterfat calculating cops7a cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Difference) ?		10mum 20days aging cofilin1 compartments cytoskeleton decline dysregulation inactivation interestingly knock lim limk1 mef mefdko occurring pcns plasticity presenilin ps1 regard remodeling rescued safely secretase shed shh1 slingshot stream	abomasum actb b2m blat butterfat calculating cops7a cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Intersection) ?