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POLR2H and POLR2C
Number of citations of the paper that reports this interaction (PMID
9201987
)
16
Data Source:
HPRD
(in vitro)
POLR2H
POLR2C
Gene Name
polymerase (RNA) II (DNA directed) polypeptide H
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
DNA-directed RNA Polymerase II, Core Complex
DNA-directed RNA Polymerase III Complex
DNA-directed RNA Polymerase I Complex
Cytosol
Nucleus
Nucleoplasm
DNA-directed RNA Polymerase II, Core Complex
Cytoplasm
Microtubule Cytoskeleton
Molecular Function
RNA Polymerase I Activity
RNA Polymerase II Activity
RNA Polymerase III Activity
DNA Binding
RNA Polymerase II Activity
DNA Binding
Protein Dimerization Activity
Biological Process
MRNA Splicing, Via Spliceosome
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Transcription From RNA Polymerase III Promoter
Transcription Elongation From RNA Polymerase III Promoter
Termination Of RNA Polymerase III Transcription
RNA Splicing
Gene Expression
Viral Process
Positive Regulation Of Type I Interferon Production
PiRNA Metabolic Process
Somatic Stem Cell Maintenance
Regulation Of Gene Expression, Epigenetic
Innate Immune Response
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Viral Transcription
MRNA Splicing, Via Spliceosome
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
RNA Splicing
Gene Expression
Viral Process
PiRNA Metabolic Process
Somatic Stem Cell Maintenance
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Regulatory RNA pathways
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
Formation of transcription-coupled NER (TC-NER) repair complex
Dual incision reaction in TC-NER
Influenza Life Cycle
RNA Polymerase III Transcription Termination
HIV elongation arrest and recovery
NoRC negatively regulates rRNA expression
Influenza Viral RNA Transcription and Replication
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation From Type 1 Promoter
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
MicroRNA (miRNA) biogenesis
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
RNA Polymerase III Transcription Initiation From Type 2 Promoter
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Abortive And Retractive Initiation
Transcription of the HIV genome
Nucleotide Excision Repair
PIWI-interacting RNA (piRNA) biogenesis
mRNA Splicing
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase II Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
HIV Infection
Formation of the Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Transcriptional regulation of pluripotent stem cells
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Innate Immune System
RNA Polymerase III Transcription Initiation
Transcriptional regulation by small RNAs
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Cytosolic sensors of pathogen-associated DNA
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Pausing and recovery of HIV elongation
Formation of the HIV-1 Early Elongation Complex
Viral Messenger RNA Synthesis
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Promoter Escape
mRNA Splicing
Formation of HIV-1 elongation complex containing HIV-1 Tat
PIWI-interacting RNA (piRNA) biogenesis
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Regulatory RNA pathways
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
Influenza Life Cycle
HIV elongation arrest and recovery
HIV Life Cycle
HIV Transcription Initiation
Influenza Viral RNA Transcription and Replication
RNA Pol II CTD phosphorylation and interaction with CE
Transcriptional regulation of pluripotent stem cells
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Transcriptional regulation by small RNAs
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
MicroRNA (miRNA) biogenesis
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Transcription-coupled NER (TC-NER)
Viral Messenger RNA Synthesis
Formation of the HIV-1 Early Elongation Complex
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
BARD1
BRCA1
NFKBIB
POLR2A
POLR2B
POLR2C
POLR2D
POLR2E
POLR2G
POLR2I
POLR2K
POLR2L
26 interactors:
ATF4
ATF7IP
C11orf58
C14orf1
CCHCR1
EEF1A1
ITCH
LRIF1
MYOG
NEDD4
NFKBIA
NUDT21
POLR2A
POLR2B
POLR2D
POLR2E
POLR2F
POLR2G
POLR2H
POLR2J
POLR2K
POLR2L
SMARCC2
STC2
TAF15
UBE2W
Entrez ID
5437
5432
HPRD ID
09082
15945
Ensembl ID
ENSG00000163882
ENSG00000102978
Uniprot IDs
C9J413
C9JBJ6
C9JCU7
C9JUA8
P52434
P19387
Q6FGR6
PDB IDs
2F3I
Enriched GO Terms of Interacting Partners
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7-methylguanosine MRNA Capping
PiRNA Metabolic Process
7-methylguanosine RNA Capping
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
Transcription Elongation From RNA Polymerase II Promoter
Somatic Stem Cell Maintenance
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
DNA-templated Transcription, Elongation
Nucleotide-excision Repair
Stem Cell Maintenance
Regulation Of Viral Process
Transcription Initiation From RNA Polymerase II Promoter
DNA Repair
DNA-templated Transcription, Initiation
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Stem Cell Development
Cellular Response To DNA Damage Stimulus
Stem Cell Differentiation
RNA Splicing
DNA Metabolic Process
MRNA Processing
NcRNA Metabolic Process
MRNA Metabolic Process
Viral Process
RNA Processing
Cellular Response To Stress
Negative Regulation Of Cell Differentiation
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Response To Stress
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Transcription, DNA-templated
Regulation Of Cell Differentiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Macromolecule Biosynthetic Process
Cell Development
7-methylguanosine MRNA Capping
PiRNA Metabolic Process
7-methylguanosine RNA Capping
Transcription Elongation From RNA Polymerase II Promoter
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
DNA-templated Transcription, Elongation
Somatic Stem Cell Maintenance
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Viral Process
Nucleotide-excision Repair
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
MRNA Splicing, Via Spliceosome
Stem Cell Maintenance
RNA Splicing, Via Transesterification Reactions
Regulation Of Viral Process
RNA Splicing
Transcription From RNA Polymerase II Promoter
Stem Cell Development
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
MRNA Processing
Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Stem Cell Differentiation
RNA Biosynthetic Process
MRNA Metabolic Process
Cellular Response To Stress
Termination Of RNA Polymerase III Transcription
Transcription Elongation From RNA Polymerase III Promoter
RNA Processing
DNA Repair
Regulation Of Type I Interferon Production
NcRNA Metabolic Process
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Regulation Of Gene Expression
RNA Metabolic Process
Negative Regulation Of Cell Differentiation
Transcription Initiation From RNA Polymerase I Promoter
Regulation Of RNA Biosynthetic Process
DNA-templated Transcription, Termination
Regulation Of RNA Metabolic Process
Transcription From RNA Polymerase I Promoter
Positive Regulation Of Type I Interferon Production
DNA Metabolic Process
Positive Regulation Of Metabolic Process
Gene Expression
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Tagcloud (Difference)
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Tagcloud (Intersection)
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