MYOD1 and ID1

Number of citations of the paper that reports this interaction (PMID 9242638)
48

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid, in vitro)

		MYOD1	ID1
Gene Name		myogenic differentiation 1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Myofibril	Nucleus Nucleoplasm Golgi Apparatus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Nuclear Hormone Receptor Binding Protein Heterodimerization Activity E-box Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Dimerization Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion	Negative Regulation Of Transcription From RNA Polymerase II Promoter Angiogenesis Endothelial Cell Morphogenesis Transcription, DNA-templated Transforming Growth Factor Beta Receptor Signaling Pathway Heart Development Circadian Rhythm Negative Regulation Of Transcription By Transcription Factor Localization BMP Signaling Pathway Protein Destabilization Collagen Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Regulation Of MAPK Cascade Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Blood Vessel Endothelial Cell Migration Negative Regulation Of Osteoblast Differentiation Regulation Of Angiogenesis Negative Regulation Of Transcription, DNA-templated Response To Antibiotic Blood Vessel Morphogenesis Lung Morphogenesis Lung Vasculature Development
Pathways		CDO in myogenesis Myogenesis	Cellular Senescence Oncogene Induced Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		61 interactors: ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 HAND1 HDAC1 HEY1 HIST1H3A HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 JUN KAT2B KAT5 KPNA3 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF3 TCF4 TWIST1	18 interactors: CASK COPB1 ELK1 ELK4 GATA4 HES1 IFI16 IKBKG MYF5 MYF6 MYOD1 MYOG PSMD4 RUNX1T1 SUV39H1 TCF12 TCF3 TCF4
Entrez ID		4654	3397
HPRD ID		01166	08980
Ensembl ID		ENSG00000129152	ENSG00000125968
Uniprot IDs		P15172	P41134
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Rhythmic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Organ Development Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Anatomical Structure Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance Organ Morphogenesis Anatomical Structure Development Cardiovascular System Development Regulation Of Cell Differentiation Heart Development Response To Growth Factor Biosynthetic Process Regulation Of Cell Cycle Developmental Process Cell Differentiation System Development Regulation Of Binding	Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Gene Expression Positive Regulation Of Skeletal Muscle Fiber Development Cell Fate Commitment Muscle Structure Development Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Striated Muscle Tissue Development Muscle Cell Fate Commitment Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myoblast Fusion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Muscle Tissue Development Regulation Of Gene Expression Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Cell Development Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Myotube Differentiation Biosynthetic Process Regulation Of Myoblast Differentiation Regulation Of Metabolic Process Regulation Of Cell Development
Tagcloud ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	accessory ae3 ae4 alphae1 alphae3 boxes counterparts deregulation differs dissect e47s endogenously enhancer enhancers exclusive heb helix hlh hpb igmicro leukemias lymphoblastic modify nih tal1 tcralpha tcralphabeta tcrdelta transactivate
Tagcloud (Difference) ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	accessory ae3 ae4 alphae1 alphae3 boxes counterparts deregulation differs dissect e47s endogenously enhancer enhancers exclusive heb helix hlh hpb igmicro leukemias lymphoblastic modify nih tal1 tcralpha tcralphabeta tcrdelta transactivate
Tagcloud (Intersection) ?