UNC93A and SLC39A7

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		UNC93A	SLC39A7
Name		unc-93 homolog A	solute carrier family 39 member 7
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Metal Ion Transmembrane Transporter Activity
	Biological Process	None	Monoatomic Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Metal Ion Transport B Cell Differentiation Transmembrane Transport Zinc Ion Transmembrane Transport Skin Epidermis Development Regulation Of Ferroptosis
Pathways		None	Zinc influx into cells by the SLC39 gene family
GWAS		Initial alcohol sensitivity ( 30276832 ) Serum metabolite levels ( 33031748 ) Urinary metabolite levels in chronic kidney disease ( 31959995 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: TNFRSF14	1 novel interactors: STARD3
Interacting Genes		22 interacting genes: ABHD16A AQP6 ATP13A1 CCL4 CD300C CDIPT FCER1G FXYD6-FXYD2 GJA8 GPR101 GPR151 LNPEP PSCA RHAG SLC35E4 SLC39A7 SLC48A1 SYNGR1 TIMMDC1 TMEM14B TMEM237 TMX2	29 interacting genes: AQP6 BIK CLCA4 CRCT1 ERCC6 GJA8 KCNF1 KRTAP1-3 KRTAP5-7 KRTAP9-2 LCE1A LCE1C LCE1F LCE2C LCE2D LCE4A LCE5A LELP1 RGS17 RSPO2 SHISAL1 SLC34A2 SMCP SPRY3 TMEM14B TNFRSF10D UNC93A WFDC12 YY1
Entrez ID		54346	7922
HPRD ID		12148	09028
Ensembl ID		ENSG00000112494	ENSG00000112473
Uniprot IDs		Q86WB7	A0A024RCX7 B4DZZ8 Q92504
PDB IDs		Not available	8GZE
GO Terms Enriched among Interactors		Membrane Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Ammonium Transmembrane Transport Ammonium Channel Activity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Carbon Dioxide Transport Transmembrane Transport One-carbon Compound Transport Nitrate Transmembrane Transporter Activity Inorganic Cation Transmembrane Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I IgE Receptor Activity Antigen Processing And Presentation Of Exogenous Peptide Antigen Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Methylammonium Transmembrane Transporter Activity CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Heme Export From Vacuole To Cytoplasm Heme Metabolic Process Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Positive Regulation Of Lymphocyte Migration Porphyrin-containing Compound Metabolic Process PH-gated Chloride Channel Activity Inorganic Ion Transmembrane Transport Nitrate Transmembrane Transport Antigen Processing And Presentation Of Exogenous Antigen Positive Regulation Of Type I Hypersensitivity Plasma Membrane Fc-epsilon Receptor I Complex Methylammonium Transport Methylammonium Transmembrane Transport Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Negative Regulation Of Adaptive Immune Memory Response Alcohol Binding Mitochondrial Membrane Pigment Metabolic Process Tetrapyrrole Metabolic Process Heme Export	Keratinization Epidermis Development Tissue Development