UNC93A and RHAG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UNC93A	RHAG
Description		unc-93 homolog A	Rh associated glycoprotein
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane Ankyrin-1 Complex
	Molecular Function	Protein Binding	Protein Binding Ammonium Channel Activity Methylammonium Transmembrane Transporter Activity Leak Channel Activity Ankyrin Binding Carbon Dioxide Transmembrane Transporter Activity
	Biological Process		Intracellular Monoatomic Ion Homeostasis Carbon Dioxide Transport Bicarbonate Transport Carbon Dioxide Transmembrane Transport Erythrocyte Development Multicellular Organismal-level Iron Ion Homeostasis Ammonium Transmembrane Transport Methylammonium Transmembrane Transport Ammonium Homeostasis Inorganic Cation Transmembrane Transport
Pathways			Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Rhesus glycoproteins mediate ammonium transport Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN)
Drugs
Diseases			Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
GWAS		Initial alcohol sensitivity ( 30276832) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995)	Alcohol dependence ( 26365420) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		22 interacting genes: ABHD16A AQP6 ATP13A1 CCL4 CD300C CDIPT FCER1G FXYD6-FXYD2 GJA8 GPR101 GPR151 LNPEP PSCA RHAG SLC35E4 SLC39A7 SLC48A1 SYNGR1 TIMMDC1 TMEM14B TMEM237 TMX2	11 interacting genes: ANK1 CD47 CREB3L3 ERGIC3 FAM209A GYPB ICAM4 LMNA SLC4A1 TEX29 UNC93A
Entrez ID		54346	6005
HPRD ID		12148	01582
Ensembl ID		ENSG00000112494	ENSG00000112077
Uniprot IDs		Q86WB7	Q02094 Q96E98
PDB IDs			7UZQ 7V0K 7V0S 8CRT 8CS9 8CSL 8CSX 8CTE
Enriched GO Terms of Interacting Partners?		Membrane Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Ammonium Transmembrane Transport Ammonium Channel Activity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Carbon Dioxide Transport Transmembrane Transport One-carbon Compound Transport Nitrate Transmembrane Transporter Activity Inorganic Cation Transmembrane Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I IgE Receptor Activity Antigen Processing And Presentation Of Exogenous Peptide Antigen Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Methylammonium Transmembrane Transporter Activity CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Heme Export From Vacuole To Cytoplasm Heme Metabolic Process Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Positive Regulation Of Lymphocyte Migration Porphyrin-containing Compound Metabolic Process PH-gated Chloride Channel Activity Inorganic Ion Transmembrane Transport Nitrate Transmembrane Transport Antigen Processing And Presentation Of Exogenous Antigen Positive Regulation Of Type I Hypersensitivity Plasma Membrane Fc-epsilon Receptor I Complex Methylammonium Transport Methylammonium Transmembrane Transport Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Negative Regulation Of Adaptive Immune Memory Response Alcohol Binding Mitochondrial Membrane Pigment Metabolic Process Tetrapyrrole Metabolic Process Heme Export	Ankyrin-1 Complex
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