ADRA1D

Name	adrenoceptor alpha 1D
Structure	No pdb structure
Interactors	8 interactors: ADRA1A FLNC LNX1 NOS1 SNTA1 SNTB1 SNTB2 SNTG1
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Adrenergic Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Positive Regulation Of MAPK Cascade Positive Regulation Of Vasoconstriction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Neuron-glial Cell Signaling
Pathways	Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events
Drugs	Amphetamine Midodrine Ranolazine Cabergoline Ropinirole Dapiprazole Dihydroergotamine Amitriptyline Alfuzosin Alfuzosin Norepinephrine Mirtazapine Phenylephrine Prochlorperazine Prazosin Prazosin Imipramine Chlorpromazine Buspirone Nortriptyline Amoxapine Clonidine Doxazosin Labetalol Nicardipine Verapamil Epinephrine Phentolamine Ergotamine Tizanidine Tamsulosin Paroxetine Methoxamine Fenoldopam Dobutamine Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Ergoloid mesylate Promethazine Carvedilol Carvedilol Doxepin Desipramine Terazosin Escitalopram Pergolide Bromocriptine Quetiapine Mephentermine Methotrimeprazine Dextroamphetamine Dronedarone R450 Epicept NP-1 Sertindole Mianserin Pizotifen Silodosin Ocaperidone Droxidopa Xylometazoline Tetryzoline Perospirone Dosulepin Etoperidone Lorpiprazole Cirazoline Synephrine Arotinolol Moxisylyte Aranidipine Pipamperone Racepinephrine Dihydroergocornine DL-Methylephedrine Indigotindisulfonic acid Tiapride Dihydroergocristine
GWAS	Paneth cell defects in Crohn's disease ( 28352666 ) Preeclampsia ( 23551011 ) Sense of smell ( 26632684 )
Entrez ID	146
HPRD ID	00079
Ensembl ID	ENSG00000171873
Uniprot IDs	B0ZBE0 P25100
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Dystrophin-associated Glycoprotein Complex Sarcolemma Actin Binding Muscle Contraction Calmodulin Binding Structural Molecule Activity Syntrophin Complex Muscle System Process PDZ Domain Binding Cytoskeleton Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of The Force Of Heart Contraction Regulation Of Heart Contraction Sodium Channel Regulator Activity Regulation Of Membrane Repolarization Regulation Of Sodium Ion Transmembrane Transport Regulation Of Blood Circulation Protein-containing Complex Regulation Of Action Potential Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Regulation Of Sodium Ion Transport Caveola Regulation Of Cardiac Muscle Contraction Anchoring Junction Cytoplasm Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Regulation Of Membrane Potential Phospholipase C-activating Adrenergic Receptor Signaling Pathway Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Striated Muscle Contraction Focal Adhesion Synaptic Signaling By Nitric Oxide Regulation Of Heart Rate Pilomotor Reflex Alpha1-adrenergic Receptor Activity Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Nitric-oxide Synthase Activity Negative Regulation Of Serotonin Uptake Tetrahydrobiopterin Binding Positive Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Peptidyl-cysteine S-nitrosylase Activity Z Disc Regulation Of System Process Transmembrane Transporter Binding Regulation Of Serotonin Uptake Blood Vessel Diameter Maintenance Neuron-glial Cell Signaling Regulation Of Tube Size