POLE3 and POLE4

Number of citations of the paper that reports this interaction (PMID 10801849)
20

Data Source:
HPRD (in vitro)

		POLE3	POLE4
Gene Name		polymerase (DNA directed), epsilon 3, accessory subunit	polymerase (DNA-directed), epsilon 4, accessory subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Ada2/Gcn5/Ada3 Transcription Activator Complex Epsilon DNA Polymerase Complex	Nucleus Ada2/Gcn5/Ada3 Transcription Activator Complex Epsilon DNA Polymerase Complex
	Molecular Function	DNA-directed DNA Polymerase Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	DNA-directed DNA Polymerase Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	DNA Replication Histone H3 Acetylation DNA Biosynthetic Process	Histone H3 Acetylation DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP BAZ1A CHRAC1 DR1 DRAP1 POLE POLE4 SMARCA5	6 interactors: HSPA13 NFYB POLE POLE2 POLE3 UBE3A
Entrez ID		54107	56655
HPRD ID		06274	16238
Ensembl ID		ENSG00000148229
Uniprot IDs		Q9NRF9	Q9NR33
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Modification Chromatin Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA Biosynthetic Process DNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Remodeling Biosynthetic Process Histone H3 Acetylation Organelle Organization DNA-dependent DNA Replication Histone Acetylation Synaptic Growth At Neuromuscular Junction Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Collateral Sprouting In Absence Of Injury Cellular Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition RNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter Nucleosome Positioning Axon Choice Point Recognition Base-excision Repair, Gap-filling Gene Expression Neuron Remodeling Peptidyl-lysine Modification Negative Regulation Of Cellular Metabolic Process DNA Replication Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Chromatin Silencing At RDNA DNA Synthesis Involved In DNA Repair Nucleotide-excision Repair, DNA Gap Filling Cellular Copper Ion Homeostasis Regulation Of Transcription, DNA-templated Telomere Maintenance Via Semi-conservative Replication Regulation Of Nucleic Acid-templated Transcription	DNA Biosynthetic Process Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Recombination DNA Replication Telomere Maintenance Via Telomere Lengthening DNA Replication Initiation Transcription-coupled Nucleotide-excision Repair Telomere Maintenance Nucleotide-excision Repair DNA-dependent DNA Replication Sperm Entry G1/S Transition Of Mitotic Cell Cycle Chromosome Organization Error-prone Translesion Synthesis DNA Metabolic Process DNA Recombination Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Base-excision Repair, Gap-filling Translesion Synthesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA Synthesis Involved In DNA Repair Prostate Gland Growth Postreplication Repair Nucleobase-containing Compound Metabolic Process DNA Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Mitotic Cell Cycle Process Protein K48-linked Ubiquitination Cellular Homeostasis Cellular Nitrogen Compound Metabolic Process Androgen Receptor Signaling Pathway Protein Autoubiquitination Mitotic Cell Cycle Histone H3 Acetylation Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Base-excision Repair Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cellular Metabolic Process Ovarian Follicle Development Prostate Gland Development Intracellular Steroid Hormone Receptor Signaling Pathway
Tagcloud ?		acetylase acetylating ada ada2 ada3 atac chrac17 coregulators fam48a gcn5 hereafter invertebrates machineries map3 map3k7 mbip nc2beta p38ip paralogous pole4 saga spt spt20 spt3 staf36 staga taf9 wdr5 yeats2	acetylase acetylating ada ada2 ada3 atac chrac17 coregulators fam48a gcn5 hereafter invertebrates machineries map3 map3k7 mbip nc2beta p38ip paralogous pole3 saga spt spt20 spt3 staf36 staga taf9 wdr5 yeats2
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		acetylase acetylating ada ada2 ada3 atac chrac17 coregulators fam48a gcn5 hereafter invertebrates machineries map3 map3k7 mbip nc2beta p38ip paralogous pole3 pole4 saga spt spt20 spt3 staf36 staga taf9 wdr5 yeats2