POLE3 and CHRAC1

Number of citations of the paper that reports this interaction (PMID 10880450)
52

Data Source:
HPRD (in vivo)

		POLE3	CHRAC1
Gene Name		polymerase (DNA directed), epsilon 3, accessory subunit	chromatin accessibility complex 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Ada2/Gcn5/Ada3 Transcription Activator Complex Epsilon DNA Polymerase Complex	Epsilon DNA Polymerase Complex CHRAC
	Molecular Function	DNA-directed DNA Polymerase Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	DNA Binding DNA-directed DNA Polymerase Activity Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	DNA Replication Histone H3 Acetylation DNA Biosynthetic Process	Chromatin Remodeling DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP BAZ1A CHRAC1 DR1 DRAP1 POLE POLE4 SMARCA5	5 interactors: APP BAZ1A FAM9B POLE3 SMARCA5
Entrez ID		54107	54108
HPRD ID		06274	06275
Ensembl ID		ENSG00000148229	ENSG00000104472
Uniprot IDs		Q9NRF9	Q9NRG0
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Modification Chromatin Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA Biosynthetic Process DNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Remodeling Biosynthetic Process Histone H3 Acetylation Organelle Organization DNA-dependent DNA Replication Histone Acetylation Synaptic Growth At Neuromuscular Junction Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Collateral Sprouting In Absence Of Injury Cellular Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition RNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter Nucleosome Positioning Axon Choice Point Recognition Base-excision Repair, Gap-filling Gene Expression Neuron Remodeling Peptidyl-lysine Modification Negative Regulation Of Cellular Metabolic Process DNA Replication Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Chromatin Silencing At RDNA DNA Synthesis Involved In DNA Repair Nucleotide-excision Repair, DNA Gap Filling Cellular Copper Ion Homeostasis Regulation Of Transcription, DNA-templated Telomere Maintenance Via Semi-conservative Replication Regulation Of Nucleic Acid-templated Transcription	Chromatin Modification Chromatin Organization Chromosome Organization Synaptic Growth At Neuromuscular Junction DNA Metabolic Process Chromatin Remodeling Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition DNA Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Nucleosome Positioning Axon Choice Point Recognition Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Silencing At RDNA Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle CENP-A Containing Nucleosome Assembly Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Histone Exchange Chromatin Silencing DNA Replication-independent Nucleosome Assembly Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Histone H3 Acetylation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Centromere Complex Assembly Organelle Organization Axon Cargo Transport Mating Neuromuscular Junction Development RNA Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition
Tagcloud ?		acetylase acetylating ada ada2 ada3 atac chrac17 coregulators fam48a gcn5 hereafter invertebrates machineries map3 map3k7 mbip nc2beta p38ip paralogous pole4 saga spt spt20 spt3 staf36 staga taf9 wdr5 yeats2	17q 17q12 17q23 8q 8q23 8q24 agar amplicon amplicons amplifications amplified anchorage belonging boosted carry clonogenic colonies driver eif3h encode genomics grb7 indeed investigating overexpressed presenting rad21 screens tanc2
Tagcloud (Difference) ?		acetylase acetylating ada ada2 ada3 atac chrac17 coregulators fam48a gcn5 hereafter invertebrates machineries map3 map3k7 mbip nc2beta p38ip paralogous pole4 saga spt spt20 spt3 staf36 staga taf9 wdr5 yeats2	17q 17q12 17q23 8q 8q23 8q24 agar amplicon amplicons amplifications amplified anchorage belonging boosted carry clonogenic colonies driver eif3h encode genomics grb7 indeed investigating overexpressed presenting rad21 screens tanc2
Tagcloud (Intersection) ?