CLIC6 and OXR1

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		CLIC6	OXR1
Description		chloride intracellular channel 6	oxidation resistance 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Monoatomic Ion Channel Complex Chloride Channel Complex Extracellular Exosome	Nucleus Nucleolus Mitochondrion
	Molecular Function	Chloride Channel Activity Oxidoreductase Activity D2 Dopamine Receptor Binding D3 Dopamine Receptor Binding D4 Dopamine Receptor Binding	Protein Binding Oxidoreductase Activity
	Biological Process	Monoatomic Ion Transport Chloride Transport Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport	Response To Oxidative Stress Adult Walking Behavior Negative Regulation Of Neuron Apoptotic Process Neuron Apoptotic Process Cellular Response To Hydroperoxide Negative Regulation Of Cellular Response To Oxidative Stress
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851) Breast cancer ( 31757997) Epigenetic age acceleration in alcohol use disorder ( 31466081) Hippocampal volume ( 29274321) Psoriasis ( 25903422) Waist-to-hip ratio adjusted for BMI ( 28552196)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intraocular pressure ( 29785010) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Post bronchodilator FEV1 in COPD ( 26634245) Reticulocyte count ( 32888494)
Interacting Genes		27 interacting genes: ACTB ALDH5A1 ARG2 ATRX CLIC4 DRD2 DRD3 DRD4 EEF1A1 FCGR1A GFPT2 HUWE1 LGI1 MYO1E NFE2L2 NISCH OXR1 PGK1 PKM PPRC1 TAF12 TUBGCP5 UBE4A ZNF18 ZNF224 ZNF234 ZNF439	3 interacting genes: CLIC6 KEAP1 LIG4
Entrez ID		54102	55074
HPRD ID		10836	16126
Ensembl ID		ENSG00000159212	ENSG00000164830
Uniprot IDs		Q96NY7	Q8N573
PDB IDs
Enriched GO Terms of Interacting Partners?		Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Dopamine Neurotransmitter Receptor Activity Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Regulation Of Dopamine Uptake Involved In Synaptic Transmission Phospholipase C-activating Dopamine Receptor Signaling Pathway Response To Histamine Synaptic Transmission, Dopaminergic Behavioral Response To Cocaine Regulation Of Neurotransmitter Uptake Arachidonate Secretion G Protein-coupled Dopamine Receptor Signaling Pathway Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Dopamine Binding Positive Regulation Of Neurotransmitter Uptake Long-chain Fatty Acid Transport Negative Regulation Of Synaptic Transmission, Glutamatergic Adult Behavior Behavioral Response To Ethanol Regulation Of Dopamine Receptor Signaling Pathway Circadian Regulation Of Gene Expression Negative Regulation Of Cellular Response To Hypoxia Negative Regulation Of Protein Secretion Prepulse Inhibition G Protein-coupled Receptor Internalization Locomotory Behavior Regulation Of Amine Transport Adult Locomotory Behavior Negative Regulation Of Cytosolic Calcium Ion Concentration Ubiquitin-ubiquitin Ligase Activity Response To Morphine Fatty Acid Transport Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Cellular Response To Oxidative Stress Canonical Glycolysis Glycolytic Process Through Glucose-6-phosphate Glycolytic Process Through Fructose-6-phosphate Regulation Of Cellular Response To Hypoxia Regulation Of Dopamine Secretion Rhythmic Process Acid Secretion Secretory Granule Lumen Glucose Catabolic Process Regulation Of Transcription By RNA Polymerase II Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Protein Transport Dopamine Metabolic Process Ficolin-1-rich Granule Lumen Regulation Of Response To Oxidative Stress Response To Amphetamine Regulation Of Cellular Response To Stress	Embryo Development Ending In Birth Or Egg Hatching Establishment Of Integrated Proviral Latency Multicellular Organism Development DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency Chordate Embryonic Development In Utero Embryonic Development DNA Ligase Activity DN2 Thymocyte Differentiation D2 Dopamine Receptor Binding D4 Dopamine Receptor Binding D3 Dopamine Receptor Binding Nucleotide-excision Repair, DNA Gap Filling DNA-dependent Protein Kinase-DNA Ligase 4 Complex Immunoglobulin V(D)J Recombination Nonhomologous End Joining Complex Negative Regulation Of Response To Oxidative Stress Double-strand Break Repair Via Classical Nonhomologous End Joining Single Strand Break Repair Lymphoid Progenitor Cell Differentiation AMP Binding Cellular Response To Lithium Ion Response To Lithium Ion V(D)J Recombination Inclusion Body Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Cellular Response To Interleukin-4 Somatic Diversification Of Immunoglobulins Involved In Immune Response Response To X-ray Response To Interleukin-4 Disordered Domain Specific Binding Regulation Of Response To Oxidative Stress Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Base-excision Repair Fibroblast Proliferation Transcription Regulator Inhibitor Activity Somatic Cell DNA Recombination T Cell Differentiation In Thymus Somatic Diversification Of Immunoglobulins Chloride Channel Complex
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