PNLIPRP1 and GDAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PNLIPRP1	GDAP1
Description		pancreatic lipase related protein 1	ganglioside induced differentiation associated protein 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Cytosol Membrane
	Molecular Function	Lipoprotein Lipase Activity Triacylglycerol Lipase Activity Calcium Ion Binding Protein Binding Phospholipase A1 Activity Lipase Activity Metal Ion Binding Carboxylic Ester Hydrolase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Biosynthetic Process Triglyceride Catabolic Process High-density Lipoprotein Particle Remodeling Cholesterol Homeostasis	Mitochondrial Fission Protein Targeting To Mitochondrion Mitochondrial Fusion Response To Retinoic Acid Cellular Response To Vitamin D
Pathways		Digestion of dietary lipid	Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS		Anger ( 24489884) Blood protein levels ( 30072576) Body mass index ( 26426971) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Loneliness (multivariate analysis) ( 27629369)	Dysmenorrheic pain ( 27454463) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 32499647) Waist circumference ( 17903300)
Interacting Genes		45 interacting genes: AQP2 ARL13B BEST2 CD79A CERS4 CPLX4 CREB3 CYB5R3 EBP ERGIC3 FAM209A FFAR2 GDAP1 GJA8 GJB5 GPR152 GPR42 GPX8 HSD17B13 KCNJ6 LEUTX LMNA LRRC25 MCFD2 MEOX2 MUC1 NDUFAF1 NEMP1 PEX12 RETREG3 SCN3B SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35H1 SLC39A2 SLC7A1 STX1A TMEM14B TMEM237 TMEM31 TMPPE TMX2 TSPAN8	10 interacting genes: ABHD16A APOD CLCN7 DCBLD2 FAM114A1 PNLIPRP1 STARD4 TMEM14B TMEM218 TUBB
Entrez ID		5407	54332
HPRD ID		05109	05963
Ensembl ID		ENSG00000187021	ENSG00000104381
Uniprot IDs		P54315	A0A6Q8PEZ4 A0A6Q8PH97 B4DIH2 Q8TB36
PDB IDs		2PPL	7AIA 7ALM 7B2G 7Q6J 7Q6K 7YWD 8A4J 8A4K
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Protein Binding	Acylglycerol Catabolic Process Cholesterol Binding Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Chloride:proton Antiporter Activity Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Lipid Transport Involved In Lipid Storage Cholesterol Transport Involved In Cholesterol Storage Positive Regulation Of Bile Acid Biosynthetic Process
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