PNLIPRP1 and NDUFAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PNLIPRP1	NDUFAF1
Description		pancreatic lipase related protein 1	NADH:ubiquinone oxidoreductase complex assembly factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol
	Molecular Function	Lipoprotein Lipase Activity Triacylglycerol Lipase Activity Calcium Ion Binding Protein Binding Phospholipase A1 Activity Lipase Activity Metal Ion Binding Carboxylic Ester Hydrolase Activity	Protein Binding Unfolded Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Biosynthetic Process Triglyceride Catabolic Process High-density Lipoprotein Particle Remodeling Cholesterol Homeostasis	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly Chaperone-mediated Protein Complex Assembly Protein-containing Complex Assembly
Pathways		Digestion of dietary lipid	Complex I biogenesis
Drugs
Diseases
GWAS		Anger ( 24489884) Blood protein levels ( 30072576) Body mass index ( 26426971) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Loneliness (multivariate analysis) ( 27629369)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Eosinophil percentage of white cells ( 27863252) Ulcerative colitis ( 23128233 28067908)
Interacting Genes		45 interacting genes: AQP2 ARL13B BEST2 CD79A CERS4 CPLX4 CREB3 CYB5R3 EBP ERGIC3 FAM209A FFAR2 GDAP1 GJA8 GJB5 GPR152 GPR42 GPX8 HSD17B13 KCNJ6 LEUTX LMNA LRRC25 MCFD2 MEOX2 MUC1 NDUFAF1 NEMP1 PEX12 RETREG3 SCN3B SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35H1 SLC39A2 SLC7A1 STX1A TMEM14B TMEM237 TMEM31 TMPPE TMX2 TSPAN8	7 interacting genes: MAGEA11 PNLIPRP1 SLC30A2 STX8 TMEM86B TMEM97 YIPF6
Entrez ID		5407	51103
HPRD ID		05109	09500
Ensembl ID		ENSG00000187021	ENSG00000137806
Uniprot IDs		P54315	Q9Y375
PDB IDs		2PPL
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Protein Binding	Zinc Ion Import Into Lysosome Zinc Export Across Plasma Membrane Vacuolar Transmembrane Transport Zinc Ion Import Into Organelle Monoatomic Cation Transmembrane Transporter Activity Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Late Endosome Response To Zinc Ion Zinc Ion Import Into Zymogen Granule Export Across Plasma Membrane Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle D-lysine 5,6-aminomutase Activity Sterol Homeostasis Cholesterol Homeostasis Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Antiporter Activity Lysosomal Transport Lysosome Zinc:proton Antiporter Activity Positive Regulation Of Lipoprotein Transport Telomerase Holoenzyme Complex Assembly Intracellular Transport Preribosome Binding Lipoprotein Lipase Activity Lipid Homeostasis Vacuolar Transport Secretory Vesicle Chloride Channel Inhibitor Activity Trans-Golgi Network Rough Endoplasmic Reticulum Membrane Regulation Of Intracellular Cholesterol Transport Regulation Of Intracellular Lipid Transport Golgi Trans Cisterna Golgi Medial Cisterna Positive Regulation Of Protein Binding Intestinal Epithelial Cell Development Regulation Of Protein Localization To Nucleolus
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