NDUFAF1 and SLC30A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NDUFAF1	SLC30A2
Description		NADH:ubiquinone oxidoreductase complex assembly factor 1	solute carrier family 30 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Lysosome Lysosomal Membrane Endosome Late Endosome Plasma Membrane Endosome Membrane Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Zymogen Granule Membrane Secretory Vesicle
	Molecular Function	Protein Binding Unfolded Protein Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Monoatomic Cation Transmembrane Transporter Activity Antiporter Activity Identical Protein Binding Metal Ion Binding Zinc:proton Antiporter Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly Chaperone-mediated Protein Complex Assembly Protein-containing Complex Assembly	Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Response To Zinc Ion Transmembrane Transport Zinc Ion Import Into Organelle Zinc Ion Transmembrane Transport Zinc Export Across Plasma Membrane Zinc Ion Import Into Secretory Vesicle Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Lysosome Zinc Ion Import Into Mitochondrion
Pathways		Complex I biogenesis	Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Eosinophil percentage of white cells ( 27863252) Ulcerative colitis ( 23128233 28067908)
Interacting Genes		7 interacting genes: MAGEA11 PNLIPRP1 SLC30A2 STX8 TMEM86B TMEM97 YIPF6	67 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 ERGIC3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2
Entrez ID		51103	7780
HPRD ID		09500	18057
Ensembl ID		ENSG00000137806	ENSG00000158014
Uniprot IDs		Q9Y375	Q9BRI3
PDB IDs
Enriched GO Terms of Interacting Partners?		Zinc Ion Import Into Lysosome Zinc Export Across Plasma Membrane Vacuolar Transmembrane Transport Zinc Ion Import Into Organelle Monoatomic Cation Transmembrane Transporter Activity Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Late Endosome Response To Zinc Ion Zinc Ion Import Into Zymogen Granule Export Across Plasma Membrane Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle D-lysine 5,6-aminomutase Activity Sterol Homeostasis Cholesterol Homeostasis Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Antiporter Activity Lysosomal Transport Lysosome Zinc:proton Antiporter Activity Positive Regulation Of Lipoprotein Transport Telomerase Holoenzyme Complex Assembly Intracellular Transport Preribosome Binding Lipoprotein Lipase Activity Lipid Homeostasis Vacuolar Transport Secretory Vesicle Chloride Channel Inhibitor Activity Trans-Golgi Network Rough Endoplasmic Reticulum Membrane Regulation Of Intracellular Cholesterol Transport Regulation Of Intracellular Lipid Transport Golgi Trans Cisterna Golgi Medial Cisterna Positive Regulation Of Protein Binding Intestinal Epithelial Cell Development Regulation Of Protein Localization To Nucleolus	Membrane Transmembrane Transport Plasma Membrane Connexin Complex Gap Junction Channel Activity Gap Junction Renal Water Transport Gap Junction Assembly Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity CCR1 Chemokine Receptor Binding Amino Acid Import Across Plasma Membrane Amino Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transport Thyroid Hormone Transmembrane Transporter Activity Metal Ion Transport Protein Binding Positive Regulation Of Immune System Process Monoatomic Cation Transport Aromatic Amino Acid Transport
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