RBM47 and MIRLET7E

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		RBM47	MIRLET7E
Description		RNA binding motif protein 47	microRNA let-7e
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Apolipoprotein B MRNA Editing Enzyme Complex	Extracellular Space RISC Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Enzyme Binding Enzyme-substrate Adaptor Activity	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Hematopoietic Progenitor Cell Differentiation MRNA Processing RNA Splicing Cytidine To Uridine Editing Positive Regulation Of Interleukin-10 Production Low-density Lipoprotein Particle Clearance Positive Regulation Of Type I Interferon-mediated Signaling Pathway 3'-UTR-mediated MRNA Stabilization	MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Body mass index (change over time) ( 25133637) Carotid intima media thickness x smoking interaction ( 32117412) Diastolic blood pressure ( 27618447) Hypertension ( 27618447) Monocyte count ( 32888494) Mosquito bite size ( 28199695) Systolic blood pressure ( 27618447) Total cholesterol levels ( 30275531) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		17 interacting genes: C10orf55 C1orf94 CAMK2A CELF5 HIVEP1 HSFY1 MIR16-1 MIR29A MIR29B1 MIRLET7E MIRLET7F1 NUTM2F OTX2 PCBP3 PRR13 RBFOX1 ZNF385C	105 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PLRG1 PRMT1 PTBP1 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RBM47 RBM5 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		54502	406887
HPRD ID		13373
Ensembl ID		ENSG00000163694	ENSG00000198972
Uniprot IDs		A0AV96 B7Z8Z7
PDB IDs		2DIS
Enriched GO Terms of Interacting Partners?		MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Mesenchymal Stem Cell Proliferation Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Circulating Fibrinogen Levels Regulation Of Amyloid-beta Formation MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Apoptotic Mitochondrial Changes Regulation Of Membrane Permeability Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Amide Metabolic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Extracellular Vesicle Negative Regulation Of Collagen Biosynthetic Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Mitochondrial Membrane Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Stem Cell Proliferation LncRNA Binding Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Collagen Biosynthetic Process Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Translation Peptidyl-threonine Autophosphorylation C-rich Single-stranded DNA Binding Regulation Of Endothelial Cell Migration Negative Regulation Of Placenta Blood Vessel Development Regulation Of Collagen Metabolic Process Negative Regulation Of Intestinal Epithelial Cell Development	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Metabolic Process MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Binding Regulation Of MRNA Metabolic Process Macromolecule Metabolic Process Spliceosomal Complex Catalytic Step 2 Spliceosome Regulation Of RNA Splicing Nucleoplasm Nucleus Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex MiRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Ribonucleoprotein Complex MRNA 3'-UTR Binding Regulation Of Translation Regulation Of RNA Stability Regulation Of MRNA Stability Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Protein-RNA Complex Assembly Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Positive Regulation Of Gene Expression TRNA Aminoacylation TRNA Metabolic Process U2 SnRNP Regulation Of Primary Metabolic Process Spliceosomal Complex Assembly Positive Regulation Of Cytoplasmic Translation
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