RBM47 and MIR16-1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		RBM47	MIR16-1
Description		RNA binding motif protein 47	microRNA 16-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Apolipoprotein B MRNA Editing Enzyme Complex	Extracellular Space RISC Complex Extracellular Exosome Extracellular Vesicle
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Enzyme Binding Enzyme-substrate Adaptor Activity	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Hematopoietic Progenitor Cell Differentiation MRNA Processing RNA Splicing Cytidine To Uridine Editing Positive Regulation Of Interleukin-10 Production Low-density Lipoprotein Particle Clearance Positive Regulation Of Type I Interferon-mediated Signaling Pathway 3'-UTR-mediated MRNA Stabilization	Branching Involved In Blood Vessel Morphogenesis Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Angiogenesis MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Translation Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Inflammatory Response Cellular Response To Glucose Stimulus Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Placenta Blood Vessel Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Trophoblast Cell Migration Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Mesenchymal Stem Cell Proliferation Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Connective Tissue Replacement Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Regulation Of Glucosylceramide Catabolic Process Negative Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Body mass index (change over time) ( 25133637) Carotid intima media thickness x smoking interaction ( 32117412) Diastolic blood pressure ( 27618447) Hypertension ( 27618447) Monocyte count ( 32888494) Mosquito bite size ( 28199695) Systolic blood pressure ( 27618447) Total cholesterol levels ( 30275531) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		17 interacting genes: C10orf55 C1orf94 CAMK2A CELF5 HIVEP1 HSFY1 MIR16-1 MIR29A MIR29B1 MIRLET7E MIRLET7F1 NUTM2F OTX2 PCBP3 PRR13 RBFOX1 ZNF385C	71 interacting genes: APOBEC3B C1QBP CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LIN28A LRPPRC MATR3 MSI2 NONO NUDT21 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 RARS1 RBFOX2 RBM14 RBM47 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYNCRIP TAF15 TRA2A TRA2B UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		54502	406950
HPRD ID		13373
Ensembl ID		ENSG00000163694	ENSG00000208006
Uniprot IDs		A0AV96 B7Z8Z7
PDB IDs		2DIS
Enriched GO Terms of Interacting Partners?		MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Mesenchymal Stem Cell Proliferation Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Circulating Fibrinogen Levels Regulation Of Amyloid-beta Formation MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Apoptotic Mitochondrial Changes Regulation Of Membrane Permeability Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Amide Metabolic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Extracellular Vesicle Negative Regulation Of Collagen Biosynthetic Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Mitochondrial Membrane Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Stem Cell Proliferation LncRNA Binding Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Collagen Biosynthetic Process Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Translation Peptidyl-threonine Autophosphorylation C-rich Single-stranded DNA Binding Regulation Of Endothelial Cell Migration Negative Regulation Of Placenta Blood Vessel Development Regulation Of Collagen Metabolic Process Negative Regulation Of Intestinal Epithelial Cell Development	RNA Binding Nucleic Acid Binding RNA Processing RNA Splicing RNA Metabolic Process MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleus Macromolecule Metabolic Process Ribonucleoprotein Complex Nucleoplasm Negative Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Spliceosomal Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Catalytic Step 2 Spliceosome Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Translation MRNA Stabilization MRNA 3'-UTR Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Cytoplasmic Stress Granule Positive Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of Macromolecule Metabolic Process Regulation Of RNA Stability Positive Regulation Of Cytoplasmic Translation MiRNA Binding Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Translation Negative Regulation Of Catabolic Process Negative Regulation Of Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome CRD-mediated MRNA Stabilization MRNA 5'-UTR Binding Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process
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