RBM47 and MIRLET7F1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		RBM47	MIRLET7F1
Description		RNA binding motif protein 47	microRNA let-7f-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Apolipoprotein B MRNA Editing Enzyme Complex	Extracellular Space RISC Complex Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Enzyme Binding Enzyme-substrate Adaptor Activity	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Hematopoietic Progenitor Cell Differentiation MRNA Processing RNA Splicing Cytidine To Uridine Editing Positive Regulation Of Interleukin-10 Production Low-density Lipoprotein Particle Clearance Positive Regulation Of Type I Interferon-mediated Signaling Pathway 3'-UTR-mediated MRNA Stabilization	Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of TOR Signaling Negative Regulation Of Interleukin-17 Production MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Apoptotic Process Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Cellular Response To Amyloid-beta
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Body mass index (change over time) ( 25133637) Carotid intima media thickness x smoking interaction ( 32117412) Diastolic blood pressure ( 27618447) Hypertension ( 27618447) Monocyte count ( 32888494) Mosquito bite size ( 28199695) Systolic blood pressure ( 27618447) Total cholesterol levels ( 30275531) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		17 interacting genes: C10orf55 C1orf94 CAMK2A CELF5 HIVEP1 HSFY1 MIR16-1 MIR29A MIR29B1 MIRLET7E MIRLET7F1 NUTM2F OTX2 PCBP3 PRR13 RBFOX1 ZNF385C	93 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CELF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM47 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		54502	406888
HPRD ID		13373
Ensembl ID		ENSG00000163694	ENSG00000199072
Uniprot IDs		A0AV96 B7Z8Z7
PDB IDs		2DIS
Enriched GO Terms of Interacting Partners?		MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Mesenchymal Stem Cell Proliferation Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Circulating Fibrinogen Levels Regulation Of Amyloid-beta Formation MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Apoptotic Mitochondrial Changes Regulation Of Membrane Permeability Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Amide Metabolic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Extracellular Vesicle Negative Regulation Of Collagen Biosynthetic Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Mitochondrial Membrane Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Stem Cell Proliferation LncRNA Binding Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Collagen Biosynthetic Process Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Translation Peptidyl-threonine Autophosphorylation C-rich Single-stranded DNA Binding Regulation Of Endothelial Cell Migration Negative Regulation Of Placenta Blood Vessel Development Regulation Of Collagen Metabolic Process Negative Regulation Of Intestinal Epithelial Cell Development	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding MRNA Processing Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Macromolecule Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleus MiRNA Binding Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule RNA Splicing, Via Transesterification Reactions Regulation Of Translation Negative Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Nucleoplasm Ribonucleoprotein Complex Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Stability Spliceosomal Complex Regulation Of MRNA Stability Regulation Of MRNA Processing Catalytic Step 2 Spliceosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Macromolecule Metabolic Process MRNA Stabilization Negative Regulation Of RNA Catabolic Process MiRNA Processing Negative Regulation Of Macromolecule Metabolic Process RNA Stabilization Regulation Of Metabolic Process Negative Regulation Of Translation TRNA Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Ligase Activity Regulation Of Alternative MRNA Splicing, Via Spliceosome
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