ATP7B and DCTN4

Number of citations of the paper that reports this interaction (PMID 16554302)
14

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (in vivo, two hybrid)

		ATP7B	DCTN4
Gene Name		ATPase, Cu++ transporting, beta polypeptide	dynactin 4 (p62)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Mitochondrion Late Endosome Trans-Golgi Network Integral Component Of Plasma Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Basolateral Plasma Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Dynactin Complex
	Molecular Function	Copper-exporting ATPase Activity Copper Ion Binding Protein Binding ATP Binding	Protein N-terminus Binding
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Cellular Zinc Ion Homeostasis Lactation Metabolic Process Copper Ion Import Intracellular Copper Ion Transport Ion Transmembrane Transport Response To Copper Ion Sequestering Of Calcium Ion Transmembrane Transport Copper Ion Export	Nuclear Migration Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		Ion transport by P-type ATPases Ion channel transport	MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ATOX1 DCTN4 HP ZBTB16	6 interactors: ACTR1A ATP7B CALCOCO2 GOLGA2 MTUS2 PNMA1
Entrez ID		540	51164
HPRD ID		06050	13126
Ensembl ID		ENSG00000123191	ENSG00000132912
Uniprot IDs		B7ZLR4 E7ET55 F5H562 F5H748 P35670	Q9NSJ5 Q9UJW0
PDB IDs		2ARF 2EW9 2KOY 2LQB 2ROP
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Hydrogen Peroxide Catabolic Process Response To Reactive Oxygen Species Intracellular Copper Ion Transport Negative Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of NK T Cell Differentiation Male Germ-line Stem Cell Asymmetric Division Regulation Of Hydrogen Peroxide Metabolic Process Copper Ion Transmembrane Transport Response To Oxidative Stress Nuclear Migration Immune System Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Localization Positive Regulation Of Cell Death Negative Regulation Of Oxidoreductase Activity Establishment Of Nucleus Localization Copper Ion Transport Regulation Of Response To Reactive Oxygen Species Positive Regulation Of Chondrocyte Differentiation	Copper Ion Export Sequestering Of Calcium Ion Intracellular Copper Ion Transport Sequestering Of Metal Ion Copper Ion Transmembrane Transport Copper Ion Import Cellular Zinc Ion Homeostasis Zinc Ion Homeostasis Cellular Copper Ion Homeostasis Copper Ion Homeostasis Response To Copper Ion Copper Ion Transport Immune System Process Inflammatory Response To Antigenic Stimulus
Tagcloud ?		abcb1 abcg2 arg72pro arg952lys asp1853asn atm backgroundovarian chances conclusionsthe emphasized facts gstm1 gstp1 gstt1 ile1145 inverted mark mark0 markabcb1 methodsin pgr question resultsten ser406ala ser894ala underscore unfavorable val660leu xenobiotics
Tagcloud (Difference) ?		abcb1 abcg2 arg72pro arg952lys asp1853asn atm backgroundovarian chances conclusionsthe emphasized facts gstm1 gstp1 gstt1 ile1145 inverted mark mark0 markabcb1 methodsin pgr question resultsten ser406ala ser894ala underscore unfavorable val660leu xenobiotics
Tagcloud (Intersection) ?