DCTN4 and ACTR10

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		DCTN4	ACTR10
Name		dynactin subunit 4	actin related protein 10
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Stress Fiber Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Dynactin Complex Focal Adhesion Cell Cortex Sarcomere	Extracellular Region Cytoplasm Cytosol Cytoskeleton Dynactin Complex Azurophil Granule Lumen Axon Cytoplasm Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	None	Microtubule-based Movement Retrograde Axonal Transport Of Mitochondrion
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025 ) Crohn's disease ( 28067908 ) Dimensional psychopathology (Arousal) ( 29496196 ) Inflammatory bowel disease ( 28067908 ) Lung adenocarcinoma ( 28604730 )	Alcohol consumption ( 31358974 ) Brain morphology (MOSTest) ( 32665545 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 )
Interacting Genes		8 interacting genes: ACTR10 ACTR1A ATP7B CALCOCO2 GOLGA2 HMG20A MTUS2 PNMA1	7 interacting genes: ACTA1 DCTN4 HOMEZ KRT31 NAGK RXFP4 SLC13A1
Entrez ID		51164	55860
HPRD ID		13126	12420
Ensembl ID		ENSG00000132912	ENSG00000131966
Uniprot IDs		A0A0S2Z5D4 Q9UJW0	Q9NZ32
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Dynactin Complex Cytoskeleton	Structural Constituent Of Cytoskeleton Sarcomere Stress Fiber Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity N-acetylglucosamine Kinase Activity N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process Muramyl Dipeptide Kinase Activity Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Protein Linear Polyubiquitination Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway N-acetylglucosamine Catabolic Process N-acetylneuraminate Catabolic Process Galanin Receptor Activity Secondary Active Sulfate Transmembrane Transporter Activity Dynactin Complex Striated Muscle Thin Filament Sulfate Transmembrane Transport UDP-N-acetylglucosamine Biosynthetic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway N-acetylneuraminate Metabolic Process Positive Regulation Of Feeding Behavior Solute:sodium Symporter Activity UDP-N-acetylglucosamine Metabolic Process Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway