ATP7B

Gene Name		ATPase, Cu++ transporting, beta polypeptide
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Gene Ontology Annotations	Cellular Component	Golgi Membrane Mitochondrion Late Endosome Trans-Golgi Network Integral Component Of Plasma Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Basolateral Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Copper-exporting ATPase Activity Copper Ion Binding Protein Binding ATP Binding
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Cellular Zinc Ion Homeostasis Lactation Metabolic Process Copper Ion Import Intracellular Copper Ion Transport Ion Transmembrane Transport Response To Copper Ion Sequestering Of Calcium Ion Transmembrane Transport Copper Ion Export
Pathways		Ion transport by P-type ATPases Ion channel transport
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: ATOX1 DCTN4 HP ZBTB16
Entrez ID		540
HPRD ID		06050
Ensembl ID		ENSG00000123191
Uniprot IDs		B7ZLR4 E7ET55 F5H562 F5H748 P35670
PDB IDs		2ARF 2EW9 2KOY 2LQB 2ROP
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Hydrogen Peroxide Catabolic Process Response To Reactive Oxygen Species Intracellular Copper Ion Transport Negative Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of NK T Cell Differentiation Male Germ-line Stem Cell Asymmetric Division Regulation Of Hydrogen Peroxide Metabolic Process Copper Ion Transmembrane Transport Response To Oxidative Stress Nuclear Migration Immune System Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Localization Positive Regulation Of Cell Death Negative Regulation Of Oxidoreductase Activity Establishment Of Nucleus Localization Copper Ion Transport Regulation Of Response To Reactive Oxygen Species Positive Regulation Of Chondrocyte Differentiation
Tagcloud ?		abcb1 abcg2 arg72pro arg952lys asp1853asn atm backgroundovarian chances conclusionsthe emphasized facts gstm1 gstp1 gstt1 ile1145 inverted mark mark0 markabcb1 methodsin pgr question resultsten ser406ala ser894ala underscore unfavorable val660leu xenobiotics