DCTN4

Description		dynactin subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Stress Fiber Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Dynactin Complex Focal Adhesion Cell Cortex Sarcomere
	Molecular Function	Protein Binding
	Biological Process
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma ( 28604730)
Interacting Genes		8 interacting genes: ACTR10 ACTR1A ATP7B CALCOCO2 GOLGA2 HMG20A MTUS2 PNMA1
Entrez ID		51164
HPRD ID		13126
Ensembl ID		ENSG00000132912
Uniprot IDs		A0A0S2Z5D4 Q9UJW0
PDB IDs
Enriched GO Terms of Interacting Partners?		Dynactin Complex Cytoskeleton
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