MYO3A and POLR2M

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYO3A	POLR2M
Description		myosin IIIA	RNA polymerase II subunit M
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GO Annotations	Cellular Component	Photoreceptor Inner Segment Cytoplasm Cytoskeleton Myosin Complex Filopodium Filamentous Actin Stereocilium Stereocilium Tip Filopodium Tip Cell Projection Organelle	DNA-directed RNA Polymerase Complex Nucleus Nuclear Envelope RNA Polymerase II, Core Complex I Band Neuronal Cell Body Transcription Preinitiation Complex
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding Calmodulin Binding ATP Binding Kinase Activity Transferase Activity ATP Hydrolysis Activity ADP Binding Plus-end Directed Microfilament Motor Activity Protein Serine Kinase Activity	RNA Polymerase II Complex Binding Transcription Elongation Factor Activity
	Biological Process	Visual Perception Sensory Perception Of Sound Regulation Of Actin Filament Length Protein Autophosphorylation Positive Regulation Of Filopodium Assembly Cochlea Morphogenesis	Transcription Elongation By RNA Polymerase II Maintenance Of ER Location
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs		Fostamatinib
Diseases		Deafness, autosomal recessive
GWAS		Obesity-related traits ( 23251661) PR interval ( 23534349) Resting-state electroencephalogram vigilance ( 29703947) Rosacea symptom severity ( 29771307) Waist circumference adjusted for body mass index ( 28552196)	Body mass index ( 28552196) Seasonality ( 25562672)
Interacting Genes		2 interacting genes: POLR2M TGFBR1	22 interacting genes: AHSP ANKHD1 APOD CEBPG CEP126 DAPK1 DGKZ HIGD1B LRRK1 LRRK2 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		53904	81488
HPRD ID		06008	07575
Ensembl ID		ENSG00000095777	ENSG00000255529
Uniprot IDs		Q8NEV4	P0CAP2 Q6EEV4
PDB IDs		6JLE	6DRD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mesenchymal Stem Cell Proliferation Coronary Vasculature Morphogenesis Activin Binding Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Myofibroblast Differentiation Activin Receptor Complex Activin Receptor Activity, Type I Type II Transforming Growth Factor Beta Receptor Binding Ventricular Compact Myocardium Morphogenesis Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis Coronary Artery Morphogenesis Parathyroid Gland Development Positive Regulation Of Tight Junction Disassembly Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Germ Cell Migration Positive Regulation Of Extracellular Matrix Assembly Vascular Endothelial Cell Proliferation Transforming Growth Factor Beta Receptor Activity Epicardium Morphogenesis Trophoblast Cell Migration Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Endothelial Cell Activation Transforming Growth Factor Beta Receptor Activity, Type I Transforming Growth Factor Beta Ligand-receptor Complex Maintenance Of ER Location Endoplasmic Reticulum Localization Transcription Elongation Factor Activity Transmembrane Receptor Protein Serine/threonine Kinase Activity Transcription Preinitiation Complex Ventricular Trabecula Myocardium Morphogenesis I-SMAD Binding RNA Polymerase II, Core Complex Pharyngeal System Development Heart Trabecula Morphogenesis Transforming Growth Factor Beta Binding Serine/threonine Protein Kinase Complex Regulation Of Extracellular Matrix Assembly Filopodium Assembly Response To Cholesterol Negative Regulation Of Chondrocyte Differentiation Embryonic Cranial Skeleton Morphogenesis Positive Regulation Of Extracellular Matrix Organization Positive Regulation Of Filopodium Assembly Blastocyst Development Activin Receptor Signaling Pathway Cardiac Epithelial To Mesenchymal Transition I Band RNA Polymerase II Complex Binding Negative Regulation Of Cartilage Development
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