FXYD1 and PLPP1

Number of citations of the paper that reports this interaction (PubMedID 10087003)
0

Data Source:
HPRD (in vitro)

		FXYD1	PLPP1
Description		FXYD domain containing ion transport regulator 1	phospholipid phosphatase 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Membrane Apical Plasma Membrane T-tubule Sarcolemma	Plasma Membrane Caveola Membrane Apical Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Chloride Channel Activity Sodium Channel Regulator Activity Transmembrane Transporter Binding Ion Channel Regulator Activity	Diacylglycerol Diphosphate Phosphatase Activity Protein Binding Phosphatidate Phosphatase Activity Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity Lysophosphatidic Acid Phosphatase Activity Ceramide-1-phosphate Phosphatase Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Chloride Transport Muscle Contraction Regulation Of Heart Contraction Negative Regulation Of Protein Glutathionylation Regulation Of Monoatomic Ion Transport Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Sodium Ion Transmembrane Transport Chloride Transmembrane Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane	Lipid Metabolic Process Phospholipid Metabolic Process Sphingosine Metabolic Process Ceramide Metabolic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Regulation Of Lipid Metabolic Process Sphingolipid Catabolic Process Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Androgen Receptor Signaling Pathway Phospholipid Dephosphorylation
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Sphingolipid catabolism
Drugs
Diseases
GWAS			Cocaine dependence ( 31212010) Heel bone mineral density ( 28869591 30598549)
Interacting Genes		9 interacting genes: ATP1A1 ATP1B1 DMPK PAM PLPP1 PPP1CA PRKACA SLC8A1 YWHAQ	5 interacting genes: CREB3 FAHD1 FXYD1 GPR42 SSMEM1
Entrez ID		5348	8611
HPRD ID		03837	06178
Ensembl ID		ENSG00000266964	ENSG00000067113
Uniprot IDs		O00168	O14494
PDB IDs		2JO1
Enriched GO Terms of Interacting Partners?		Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cell Communication By Electrical Coupling Cell Communication Involved In Cardiac Conduction Regulation Of Striated Muscle Contraction Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Regulation Of Heart Contraction Relaxation Of Cardiac Muscle Sodium Ion Export Across Plasma Membrane Regulation Of Blood Circulation Regulation Of Muscle System Process Intracellular Potassium Ion Homeostasis Relaxation Of Muscle Intracellular Sodium Ion Homeostasis Regulation Of Metal Ion Transport Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Intracellular Monoatomic Cation Homeostasis Sodium Ion Homeostasis Potassium Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Calcium-mediated Signaling T-tubule Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Chemical Homeostasis Export Across Plasma Membrane Intracellular Signal Transduction Regulation Of System Process P-type Sodium:potassium-exchanging Transporter Activity Regulation Of Sodium Ion Transport Cellular Homeostasis Regulation Of Cardiac Muscle Contraction Regulation Of Monoatomic Ion Transmembrane Transport Extracellular Exosome Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Sodium:potassium-exchanging ATPase Complex Inorganic Cation Import Across Plasma Membrane Sarcolemma Sperm Flagellum Chemical Homeostasis Intracellular Signaling Cassette Sodium Ion Transmembrane Transport Regulation Of Transport Transmembrane Transporter Binding Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Membrane Potential Regulation Of Calcium Ion Transmembrane Transport Import Across Plasma Membrane Membrane Repolarization During Action Potential	Negative Regulation Of Protein Glutathionylation Positive Regulation Of Deacetylase Activity Fumarylpyruvate Hydrolase Activity Oxaloacetate Tautomerase Activity Acylpyruvate Hydrolase Activity Acetylpyruvate Hydrolase Activity Positive Regulation Of Monoatomic Ion Transport Oxaloacetate Decarboxylase Activity Release From Viral Latency Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity Regulation Of Cardiac Muscle Cell Membrane Potential CCR1 Chemokine Receptor Binding Oxaloacetate Metabolic Process CAMP Response Element Binding Protein Binding Sodium:potassium-exchanging ATPase Complex Regulation Of Metal Ion Transport Induction Of Positive Chemotaxis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?