FXYD1 and PPAP2A

Number of citations of the paper that reports this interaction (PMID 10087003)
4

Data Source:
HPRD (in vitro)

		FXYD1	PPAP2A
Gene Name		FXYD domain containing ion transport regulator 1	phosphatidic acid phosphatase type 2A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Sodium:potassium-exchanging ATPase Complex Chloride Channel Complex Sarcolemma	Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Binding	Phosphatidate Phosphatase Activity
	Biological Process	Chloride Transport Cellular Calcium Ion Homeostasis Muscle Contraction Regulation Of Heart Contraction Ion Transmembrane Transport Transmembrane Transport Regulation Of Cardiac Muscle Cell Membrane Potential Chloride Transmembrane Transport Positive Regulation Of Sodium Ion Export From Cell Regulation Of Sodium Ion Transmembrane Transporter Activity	Protein Dephosphorylation Lipid Metabolic Process Sphingolipid Metabolic Process Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Germ Cell Migration Regulation Of Lipid Metabolic Process Sphingolipid Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Small Molecule Metabolic Process Phospholipid Dephosphorylation
Pathways		Ion transport by P-type ATPases Ion channel transport	Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ATP1A1 ATP1B1 DMPK PAM PPAP2A PPP1CA PRKACA YWHAQ	2 interactors: FAHD1 FXYD1
Entrez ID		5348	8611
HPRD ID		03837	06178
Ensembl ID		ENSG00000266964	ENSG00000067113
Uniprot IDs		O00168	O14494
PDB IDs		2J1I 2JO1
Enriched GO Terms of Interacting Partners?		Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cell Communication By Electrical Coupling Regulation Of Heart Contraction Cardiac Conduction Sodium Ion Export From Cell Regulation Of Cardiac Muscle Contraction Sodium Ion Export Regulation Of Striated Muscle Contraction Cellular Potassium Ion Homeostasis Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Cellular Metal Ion Homeostasis Cellular Sodium Ion Homeostasis Relaxation Of Cardiac Muscle Cellular Cation Homeostasis Membrane Repolarization Cellular Ion Homeostasis Potassium Ion Homeostasis Metal Ion Homeostasis Regulation Of Muscle Contraction Cellular Chemical Homeostasis Ion Homeostasis Triglyceride Catabolic Process Relaxation Of Muscle Potassium Ion Import Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Sodium Ion Homeostasis Acylglycerol Catabolic Process Regulation Of The Force Of Heart Contraction Cellular Homeostasis Cardiac Muscle Cell Action Potential Cellular Calcium Ion Homeostasis Regulation Of Metabolic Process Membrane Organization Chemical Homeostasis Calcium Ion Homeostasis Cardiac Muscle Contraction Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transport Heart Contraction Nuclear Envelope Organization Response To Abiotic Stimulus Endomembrane System Organization Striated Muscle Contraction Positive Regulation Of Dense Core Granule Biogenesis Action Potential Dephosphorylation Calcium-mediated Signaling Triglyceride Metabolic Process	Positive Regulation Of Sodium Ion Export From Cell Regulation Of Cardiac Muscle Cell Membrane Potential Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Regulation Of Sodium Ion Transport Positive Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport Chloride Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Heart Contraction
Tagcloud ?		5k 5na alpha1 alpha1beta1 alpha2 alpha2beta1 alphabeta c12e8 detergent glycero histidine k0 kmatp oleoyl ouabain pastoris phophatidylserine phosphatidyl phospholipids pichia reconstituted somewhat sops stabilizes stearoyl suboptimal tm10 tm8 tm9
Tagcloud (Difference) ?		5k 5na alpha1 alpha1beta1 alpha2 alpha2beta1 alphabeta c12e8 detergent glycero histidine k0 kmatp oleoyl ouabain pastoris phophatidylserine phosphatidyl phospholipids pichia reconstituted somewhat sops stabilizes stearoyl suboptimal tm10 tm8 tm9
Tagcloud (Intersection) ?