FXYD1

Name	FXYD domain containing ion transport regulator 1
Structure
Interactors	9 interactors: ATP1A1 ATP1B1 DMPK PAM PLPP1 PPP1CA PRKACA SLC8A1 YWHAQ
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Membrane Apical Plasma Membrane T-tubule Sarcolemma
	Molecular Function	Chloride Channel Activity Sodium Channel Regulator Activity Transmembrane Transporter Binding Ion Channel Regulator Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Chloride Transport Muscle Contraction Regulation Of Heart Contraction Negative Regulation Of Protein Glutathionylation Regulation Of Monoatomic Ion Transport Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of Sodium Ion Transmembrane Transport Chloride Transmembrane Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane
Pathways	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
GWAS	No GWAS studies recorded
Entrez ID	5348
HPRD ID	03837
Ensembl ID	ENSG00000266964
Uniprot IDs	O00168
PDB IDs	2JO1
GO Terms Enriched among Interactors ?	Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cell Communication By Electrical Coupling Cell Communication Involved In Cardiac Conduction Regulation Of Striated Muscle Contraction Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Regulation Of Heart Contraction Relaxation Of Cardiac Muscle Sodium Ion Export Across Plasma Membrane Regulation Of Blood Circulation Regulation Of Muscle System Process Intracellular Potassium Ion Homeostasis Relaxation Of Muscle Intracellular Sodium Ion Homeostasis Regulation Of Metal Ion Transport Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Intracellular Monoatomic Cation Homeostasis Sodium Ion Homeostasis Potassium Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Calcium-mediated Signaling T-tubule Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Chemical Homeostasis Export Across Plasma Membrane Intracellular Signal Transduction Regulation Of System Process P-type Sodium:potassium-exchanging Transporter Activity Regulation Of Sodium Ion Transport Cellular Homeostasis Regulation Of Cardiac Muscle Contraction Regulation Of Monoatomic Ion Transmembrane Transport Extracellular Exosome Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Sodium:potassium-exchanging ATPase Complex Inorganic Cation Import Across Plasma Membrane Sarcolemma Sperm Flagellum Chemical Homeostasis Intracellular Signaling Cassette Sodium Ion Transmembrane Transport Regulation Of Transport Transmembrane Transporter Binding Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Membrane Potential Regulation Of Calcium Ion Transmembrane Transport Import Across Plasma Membrane Membrane Repolarization During Action Potential