PLPP1

Description		phospholipid phosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Caveola Membrane Apical Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Diacylglycerol Diphosphate Phosphatase Activity Protein Binding Phosphatidate Phosphatase Activity Hydrolase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity Lysophosphatidic Acid Phosphatase Activity Ceramide-1-phosphate Phosphatase Activity
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Sphingosine Metabolic Process Ceramide Metabolic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Regulation Of Lipid Metabolic Process Sphingolipid Catabolic Process Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Androgen Receptor Signaling Pathway Phospholipid Dephosphorylation
Pathways		Sphingolipid catabolism
Drugs
Diseases
GWAS		Cocaine dependence ( 31212010) Heel bone mineral density ( 28869591 30598549)
Interacting Genes		5 interacting genes: CREB3 FAHD1 FXYD1 GPR42 SSMEM1
Entrez ID		8611
HPRD ID		06178
Ensembl ID		ENSG00000067113
Uniprot IDs		O14494
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Glutathionylation Positive Regulation Of Deacetylase Activity Fumarylpyruvate Hydrolase Activity Oxaloacetate Tautomerase Activity Acylpyruvate Hydrolase Activity Acetylpyruvate Hydrolase Activity Positive Regulation Of Monoatomic Ion Transport Oxaloacetate Decarboxylase Activity Release From Viral Latency Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity Regulation Of Cardiac Muscle Cell Membrane Potential CCR1 Chemokine Receptor Binding Oxaloacetate Metabolic Process CAMP Response Element Binding Protein Binding Sodium:potassium-exchanging ATPase Complex Regulation Of Metal Ion Transport Induction Of Positive Chemotaxis
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